红花五味子茎低极性化学成分的GC-MS分析

郑巍; 刘晓娟; 贾琳; 陈海生; 郭良君; 金永生

doi:10.3969/j.issn.1006-0111.2019.06.003

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红花五味子茎低极性化学成分的GC-MS分析

郑巍, 刘晓娟, 贾琳, 陈海生, 郭良君, 金永生

文章导航 > 药学实践与服务 > 2019 > 37(6): 491-494

郑巍, 刘晓娟, 贾琳, 陈海生, 郭良君, 金永生. 红花五味子茎低极性化学成分的GC-MS分析[J]. 药学实践与服务, 2019, 37(6): 491-494. doi: 10.3969/j.issn.1006-0111.2019.06.003

引用本文:

ZHENG Wei, LIU Xiaojuan, JIA Lin, CHEN Haisheng, GUO Liangjun, JIN Yongsheng. Analysis of low-polarity components from stems of Schisandra rubriflora (Franch). Rehd.et Wils by GC-MS.[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 491-494. doi: 10.3969/j.issn.1006-0111.2019.06.003

Citation:

ZHENG Wei, LIU Xiaojuan, JIA Lin, CHEN Haisheng, GUO Liangjun, JIN Yongsheng. Analysis of low-polarity components from stems of Schisandra rubriflora (Franch). Rehd.et Wils by GC-MS.[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 491-494. doi: 10.3969/j.issn.1006-0111.2019.06.003

红花五味子茎低极性化学成分的GC-MS分析

doi: 10.3969/j.issn.1006-0111.2019.06.003

1.
海军军医大学药学院, 上海 200433;解放军第九八医院药械科, 浙江湖州 313000
2.
厦门市医药研究所, 福建厦门 361003
3.
解放军第四五四医院药学部, 江苏南京 210000
4.
海军军医大学药学院, 上海 200433
5.
解放军第九八医院药械科, 浙江湖州 313000

基金项目: 国家自然基金资助项目（No.81573585）；原南京军区医学创新课题重大项目（No.14ZD02）

Analysis of low-polarity components from stems of Schisandra rubriflora (Franch). Rehd.et Wils by GC-MS.

1.
School of Pharmacy, Naval Medical University, Shanghai 200433, China;Department of Drug and Equipment, No. 98 Hospital of PLA, Huzhou 313000, China
2.
Xiamen Medicine Research Institute, Xiamen 361003, China
3.
Department of Pharmacy, No. 454 Hospital of PLA, Nanjing 210000, China
4.
School of Pharmacy, Naval Medical University, Shanghai 200433, China
5.
Department of Drug and Equipment, No. 98 Hospital of PLA, Huzhou 313000, China

摘要: 目的研究红花五味子茎低极性部位的主要化学成分。方法红花五味子茎用90%乙醇热提取，提取液用石油醚萃取得到石油醚部位，运用GC-MS法对其主要成分进行检测，所测结果与标准谱库进行分析，用峰面积归一法计算各个成分的相对含量。结果鉴定了49种化学成分，相对含量较高的有β-芹子烯，约占12.08%、顺，顺-2-甲基-3，13-十八烯醇，约占10.3%。结论红花五味子茎低极性部位化学成分主要为酯类化合物（45.94%），其次为脂肪酸（19.35%）和倍半萜（13.94%）。
- 红花五味子 /
- 低极性部位 /
- 气质联用 /
- 中药化学
Abstract: Objective To investigate the low-polarity components from the stems of Schisandra rubriflora (Franch).Rehd.et Wils. Methods Dried and grinded stems of this plant were extracted by 90% ethylalcohol,then the extraction was partitioned by petroleum ether to afford petroleum extract,which was analyzed by GC-MS and elucidated by the comparison with the standard mass spectral data.The relative contents in percentage were calculated by the area normalization method. Results 49 compounds were identified.Of them,β-selinene (12.08%),2-methyl-Z,Z-3,13-octadecadienol (10.3%) were the main components. Conclusion The main components in the low-polarity components of the stems of Schisandra rubriflora (Franch).Rehd.et Wils.were esters (45.94%),fatty acids (19.35%) and sesquiterpenoids (13.94%).
- Schisandra rubriflora (Franch) /
- low-polarity partition /
- GC-MS /
- Chinese medicinal chemistry

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红花五味子茎低极性化学成分的GC-MS分析

doi: 10.3969/j.issn.1006-0111.2019.06.003

1. 海军军医大学药学院, 上海 200433;解放军第九八医院药械科, 浙江湖州 313000

2. 厦门市医药研究所, 福建厦门 361003

3. 解放军第四五四医院药学部, 江苏南京 210000

4. 海军军医大学药学院, 上海 200433

5. 解放军第九八医院药械科, 浙江湖州 313000

基金项目: 国家自然基金资助项目（No.81573585）；原南京军区医学创新课题重大项目（No.14ZD02）

收稿日期: 2018-01-21
修回日期: 2019-07-08

关键词:

摘要: 目的研究红花五味子茎低极性部位的主要化学成分。方法红花五味子茎用90%乙醇热提取，提取液用石油醚萃取得到石油醚部位，运用GC-MS法对其主要成分进行检测，所测结果与标准谱库进行分析，用峰面积归一法计算各个成分的相对含量。结果鉴定了49种化学成分，相对含量较高的有β-芹子烯，约占12.08%、顺，顺-2-甲基-3，13-十八烯醇，约占10.3%。结论红花五味子茎低极性部位化学成分主要为酯类化合物（45.94%），其次为脂肪酸（19.35%）和倍半萜（13.94%）。

English Abstract

Analysis of low-polarity components from stems of Schisandra rubriflora (Franch). Rehd.et Wils by GC-MS.

1. School of Pharmacy, Naval Medical University, Shanghai 200433, China;Department of Drug and Equipment, No. 98 Hospital of PLA, Huzhou 313000, China

2. Xiamen Medicine Research Institute, Xiamen 361003, China

3. Department of Pharmacy, No. 454 Hospital of PLA, Nanjing 210000, China

4. School of Pharmacy, Naval Medical University, Shanghai 200433, China

5. Department of Drug and Equipment, No. 98 Hospital of PLA, Huzhou 313000, China

Received Date: 2018-01-21
Rev Recd Date: 2019-07-08

Keywords:

Abstract: Objective To investigate the low-polarity components from the stems of Schisandra rubriflora (Franch).Rehd.et Wils. Methods Dried and grinded stems of this plant were extracted by 90% ethylalcohol,then the extraction was partitioned by petroleum ether to afford petroleum extract,which was analyzed by GC-MS and elucidated by the comparison with the standard mass spectral data.The relative contents in percentage were calculated by the area normalization method. Results 49 compounds were identified.Of them,β-selinene (12.08%),2-methyl-Z,Z-3,13-octadecadienol (10.3%) were the main components. Conclusion The main components in the low-polarity components of the stems of Schisandra rubriflora (Franch).Rehd.et Wils.were esters (45.94%),fatty acids (19.35%) and sesquiterpenoids (13.94%).

引用本文:

Citation:

ZHENG Wei, LIU Xiaojuan, JIA Lin, CHEN Haisheng, GUO Liangjun, JIN Yongsheng. Analysis of low-polarity components from stems of Schisandra rubriflora (Franch). Rehd.et Wils by GC-MS.[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(6): 491-494. doi: 10.3969/j.issn.1006-0111.2019.06.003