树参属植物化学成分及药理活性研究进展

郑莉萍; 王庭芳; 熊礼燕; 邹豪; 张川

树参属植物化学成分及药理活性研究进展

1.
福建中医药大学药学院,福建福州 350108;第二军医大学药学院新药研究中心,上海 200433
2.
第二军医大学药学院新药研究中心,上海 200433

Progress of chemical constituents and pharmacological research of Dendropanax

1.
School of Pharmacy, Fujian traditional medine and pharmaceutical university, Fuzhou 350108, China;New drug research center, School of Pharmcy, Second military medical university, Shanghai 200433, China
2.
New drug research center, School of Pharmcy, Second military medical university, Shanghai 200433, China

摘要: 五加科Araliaceae树参属Dendropanax植物含有多种结构类型的化学成分,主要为多炔类,萜类,皂苷,挥发油等;用于瘫痪、偏头痛、臂丛神经炎、风湿性及类风湿性关节炎、扭伤、痈疖、小儿麻痹后遗症、月经不调等疾病的治疗,有抗心律失常、抗癌、抗菌和抗风湿、抗动脉粥样硬化、抑制酪氨酸酶的活性、抗肝炎病毒等药理活性。本文对树参属植物的化学成分及药理活性进行综述,为进一步开发利用该属植物提供参考。
- 树参属 /
- 化学成分 /
- 药理活性
Abstract: Objective To presente a view of chemical and pharmacological study on Dendropanax and lay a solid foundation for further research. Methods Relevant literature of Dendropanax were searched and summarized. Results and Conclusion The main chemical constituents of Dendropanax were essential oils, terpene, polyacetylene, saponins, etc,which had effects of anti-arrhythmic, anti-rheumatism, anti-cancer and anti-atherogenic, anti-microbial, anti-oxidant as well as liver protecting and inhibit tyrosinase activity, which could provide the evidence for further exploitation, utilization and quality control of the Materia Medica, extracts, products of Dendropanax.
- Dendropanax /
- chemical constituents /
- pharmacological activity

[1]	中国科学院中国植物志编辑委员会. 中国植物志第五十四卷[M]. 北京: 科学出版社, 1996: 58.
[2]	国家中医药管理局中华本草编委会. 中华本草第五卷[M]. 上海: 上海科学技术出版社, 1999: 754.
[3]	Otto RQ. Evolution of polyacetylenes in micromolecular evolution systematics and ecology. An essay into a novel botanical discipline[M]. New York:Spinger-Verlag Berlin Heidelbery, 1982, 62.
[4]	Lene H, Boll PM. Polyacetylenes in Araliaceae: their chemistry, biosynthesis and biological significance[J]. Phytochemistry. 1986, 25(2): 285.
[5]	Kawazu K, Noguchi H, Fujishita K, et al. Two new antifungal compounds from Dendropanax trifidus[J].Tetrahedron Lett. 1973, 14(33): 3131.
[6]	Oka K, Saito F, Yasuhara T,et al. The allergens of Dendropanax trifidus Makino and Fatsia japonica Decne. et Planch. and evaluation of cross-reactions with other plants of the Araliaceae family[J]. Contact Dermatitis, 1999, 40(4): 209.
[7]	Setzer WN, Green TJ, Whitaker KW, et al. A cytotoxic diacetylene from Dendropanax arboreus[J]. Planta Med. 1995, 5(61): 470.
[8]	Bernart MW, Cardellina JH, Balaschak MS, et al. Cytotoxic Falcarinol Oxylipins from Dendropanax arboreus[J]. J Nat Prod. 1996, 59(8): 748.
[9]	Park BY, Min BS, Oh SR, et al. Isolation and anticomplement activity of compounds from Dendropanax morbifera[J]. J. Ethnopharmacol. 2004, 90(2-3): 403.
[10]	Kazuo Yoshihara, et al. The Sesquiterpenes of Dendropanax trifidus[J]. B Chem Soc Jpn. 1978, 51(11): 3395.
[11]	Jun Cheul Ahn, Sung Ho Kim,et al, Seasonal Variations in Yields of Hwangchil Lacquer and Major Sesquiterpene Compounds from Selected Superior Individuals of Dendropanax morbifera Ldv[J]. J Plant Biol. 2003, 46(1): 38.
[12]	Setzer, William N. Essential oil composition of Dendropanax gonatopodus from Monteverde, Costa Rica. An ab initio examination of aromadendrane sesquiterpenoids[J]. Nat Prod Commun. 2008, 3(9): 1557.
[13]	Constantine GH. D:B-friedoolean-3,5-oxide in Rhododendron macrophyllum[J].Phytochemistry. 1970, 9(7): 1659.
[14]	Moriarity DM, Huang J, Yancey CA, et al. Lupeol is the cytotoxic principle in the leaf extract of Dendropanax cf. querceti[J]. Planta Med. 1998, 64(4): 370.
[15]	Chung IM, Kim MY, Park WH, et al. In Vitro Evaluation of the Antiplasmodial Activity of Dendropanax morbifera against Chloroquine-sensitive Strains of Plasmodium falciparum[J]. Phytotherapy Res. 2009, 23(11): 1634.
[16]	范仲先,保健菜-树参菜[J].资源开发与市场,2009,25(6): 537
[17]	Tanaka H, Fukuda N, Yahara S, et al. Isolation of Ginsenoside Rb1 from Kalopanax pictus by Eastern Blotting Using Antiginsenoside Rb1 Monoclonal Antibody[J]. Phytother. Res. 2005, 19(3): 255.
[18]	Ishikura N. A Survey of Anthocyanins in Fruits of Some Angiosperms[J]. Bot Mag Tokyo. 1975, 88(1): 41.
[19]	Chung IM, Seo SH, Kang EY, et al. Chemical composition and larvicidal effects of essential oil of Dendropanax morbifera against Aedes aegypti L[J]. Biochem Syst Ecol. 2009, 37(4): 470.
[20]	PINO JA, MARBOT R, PAYO A, et al. Leaf oil of Dendropanax arboreus L. from Cuba[J]. J Essent Oil Res. 2005, 17(5): 547.
[21]	Richmond JD, Agius BR, Wright BS, et al. Essential oil compositions and cytotoxic activities of Dendropanax capillaris, Oreopanax nubigenus, and Schefflera rodrigueziana from Monteverde, Costa Rica[J]. Nat Prod Commun. 2009, 4(2): 271.
[22]	黄敬耀, 刘春梅, 齐丕驺,等. 树参叶抗心律失常作用的研究[J]. 中国中药杂志,1989, 14(6): 50.
[23]	Zhang P. Antineoplastic activity of triterpenes from Alchornea Latifolia and Dendropanax cf. querceti. 211th ACS National Meeting, New Orleans, LA, March 24-28, 1996[C]. MEDI-082.
[24]	Gbolade AA, Oyedele AO, SosanMB, et al. Mosquito repellent activities of essential oils from two Nigerian Ocimum species[J]. J Trop Med Plants. 2000, 15(1): 146.
[25]	Adebayo TA, Gbolade AA, Olaifa JI. Comparative study of toxicity of essential oils to larvae of three mosquito species[J]. Niger J Nat Prod Med. 1999, 3(1): 74.
[26]	Altanlar N, Soner O, Tanker M, et al. Antimicrobial activity of some volatile oils[J]. Turkish Microbiol Soc. 1999, 29(2): 169.
[27]	Chung IM, Kim MYPark WH, et al. Antiatherogenic activity of Dendropanax morbifera essential oil in rats[J]. Pharmazie. 2009, 8(64): 547.
[28]	郭元敏, 徐有水, 刘日才. 树参麻黄防己汤治疗痹证58例[J]. 实用中医药杂志, 2007, 23(3): 152.
[29]	刘日才, 郭元敏. 树参麻木汤治疗痹证63例临床观察[J]. 中国中医药科技, 2005, 6(12): 334.

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树参属植物化学成分及药理活性研究进展

Progress of chemical constituents and pharmacological research of Dendropanax

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树参属植物化学成分及药理活性研究进展

1. 福建中医药大学药学院,福建福州 350108;第二军医大学药学院新药研究中心,上海 200433

2. 第二军医大学药学院新药研究中心,上海 200433

English Abstract

Progress of chemical constituents and pharmacological research of Dendropanax

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树参属植物化学成分及药理活性研究进展

Progress of chemical constituents and pharmacological research of Dendropanax

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树参属植物化学成分及药理活性研究进展

1. 福建中医药大学药学院,福建 福州 350108;第二军医大学药学院新药研究中心,上海 200433 2. 第二军医大学药学院新药研究中心,上海 200433

English Abstract

Progress of chemical constituents and pharmacological research of Dendropanax

全文HTML

目录

1. 福建中医药大学药学院,福建福州 350108;第二军医大学药学院新药研究中心,上海 200433

2. 第二军医大学药学院新药研究中心,上海 200433