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Volume 30 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(4): 241-247

JIANG Zhi-hui, ZHANG Da-zhi. Progress on structures and binding structures with small molecules of G-quadruplex[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 241-247.
Citation: JIANG Zhi-hui, ZHANG Da-zhi. Progress on structures and binding structures with small molecules of G-quadruplex[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 241-247.
shu

Progress on structures and binding structures with small molecules of G-quadruplex

  • Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2011-01-30
  • Rev Recd Date: 2011-05-25
  • There was a research focus for the prevention of diseases by way of binding to DNA using small molecules.The discovery of structures of G-quadruplex and its fimction related to cancer thtough modern molecular biology techniques provided a big chance for thedesignof anti-cancer drug.This article aimed to present recent advances for the struclures of G-quadruplex and these small binding molecules,which would contribute to understand these binding modes and thus provide a steady support in the rational designof anti-cancer drug.
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Progress on structures and binding structures with small molecules of G-quadruplex

  • Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2011-01-30
  • Rev Recd Date: 2011-05-25

Abstract: There was a research focus for the prevention of diseases by way of binding to DNA using small molecules.The discovery of structures of G-quadruplex and its fimction related to cancer thtough modern molecular biology techniques provided a big chance for thedesignof anti-cancer drug.This article aimed to present recent advances for the struclures of G-quadruplex and these small binding molecules,which would contribute to understand these binding modes and thus provide a steady support in the rational designof anti-cancer drug.

JIANG Zhi-hui, ZHANG Da-zhi. Progress on structures and binding structures with small molecules of G-quadruplex[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 241-247.
Citation: JIANG Zhi-hui, ZHANG Da-zhi. Progress on structures and binding structures with small molecules of G-quadruplex[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 241-247.
shu

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