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WU Jiu-jian, MENG Yue-liang, ZOU Li-hua, QU Yan. Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 206-207,234.
Citation: WU Jiu-jian, MENG Yue-liang, ZOU Li-hua, QU Yan. Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 206-207,234.

Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice

  • Received Date: 2010-12-12
  • Rev Recd Date: 2011-03-16
  • Objective To determine the active position of Bletilla colloid and offer references to the seleciton of its active composition. Methonds The crude Bletilla colloid was extracted by 70% ethanol permeating , then the petroleum ether extract,ethyl acetate exctract ,n-butyl alcohol extract and water extract were exctracted from alcohol extract in turn by petroleum,ethyl acetate,n-butyl alcohol extraction. The active position was determined by measuring the time of mice blood coagulation and hemorrhage. Results N-butanol extract and water extract from Bletilla colloid had hemostasis effect,ethyl acetate extract had the effect of prolonging the time of blood coagulation and hemorrhage. Conclusion N-butanol extract and water extract from Bletilla colloid was major active extracts played a part in hemostasis, ethyl acetate extract had the effect of invigoration the circulation of blood.
  • [1] 刘松敏,张晓霞,安治勋.白及粉治疗上消化道出血30例[J].中医药学报,2000,28(1):27. [2] 蔡春浩.中药白芨胶减少胃、十二指肠溃疡再出血临床观察[J].浙江医学,1996,18(4):225. [3] 吴震西.白及止血生肌效著[J].中医杂志,1997,38(7):389. [4] 姬庆平,周明德,刘 芳.烧伤供皮区创面应用白芨粉止血效果观察[J].新疆医科大学学报,1999,17(6):359. [5] 陆 波,徐亚敏,张汉明,等.白及不同提取部位对家兔血小板聚集的影响[J]. 解放军药学学报,2005, 21(5):330.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice

Abstract: Objective To determine the active position of Bletilla colloid and offer references to the seleciton of its active composition. Methonds The crude Bletilla colloid was extracted by 70% ethanol permeating , then the petroleum ether extract,ethyl acetate exctract ,n-butyl alcohol extract and water extract were exctracted from alcohol extract in turn by petroleum,ethyl acetate,n-butyl alcohol extraction. The active position was determined by measuring the time of mice blood coagulation and hemorrhage. Results N-butanol extract and water extract from Bletilla colloid had hemostasis effect,ethyl acetate extract had the effect of prolonging the time of blood coagulation and hemorrhage. Conclusion N-butanol extract and water extract from Bletilla colloid was major active extracts played a part in hemostasis, ethyl acetate extract had the effect of invigoration the circulation of blood.

WU Jiu-jian, MENG Yue-liang, ZOU Li-hua, QU Yan. Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 206-207,234.
Citation: WU Jiu-jian, MENG Yue-liang, ZOU Li-hua, QU Yan. Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 206-207,234.
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