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Volume 17 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1999  >  (4): 230-232

Wang Yanping, Liu Fuqiang, Wang Weidong, Liu Ge. Study on the method of dissolution test of norfloxacin Capsule[J]. Journal of Pharmaceutical Practice and Service, 1999, (4): 230-232.
Citation: Wang Yanping, Liu Fuqiang, Wang Weidong, Liu Ge. Study on the method of dissolution test of norfloxacin Capsule[J]. Journal of Pharmaceutical Practice and Service, 1999, (4): 230-232.
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Study on the method of dissolution test of norfloxacin Capsule

  • 208th Hospital, Changchun 130062

  • Received Date: 1999-03-10
  • OBJECTIVE To study the condition and method using UV-spectrophotomery for determining the concentration and dissolution of Norfloxacin capsule.METHODS The concentration of Norfloxacin capsule was detected by UV-spectrophotometry and the dissolution was detected by rotation basket method.RESULTS The iggest absorbtion was at 273nm wavelength(5μg/ml,0.4% NaOH solution).The average absorption coefficient(E1cm1%)is 1095,And the linear relationship was good(r=0 9998)In 20minutes,the dissolution rates were 80%.CONCLUSION The concentration of Norfloxacin can be detected by UV-spectrophotometry,it′s convient and rapid.It can also be wsed to detect the dvssolution of Norfloxacin capsule.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on the method of dissolution test of norfloxacin Capsule

  • 208th Hospital, Changchun 130062
  • Received Date: 1999-03-10

Abstract: OBJECTIVE To study the condition and method using UV-spectrophotomery for determining the concentration and dissolution of Norfloxacin capsule.METHODS The concentration of Norfloxacin capsule was detected by UV-spectrophotometry and the dissolution was detected by rotation basket method.RESULTS The iggest absorbtion was at 273nm wavelength(5μg/ml,0.4% NaOH solution).The average absorption coefficient(E1cm1%)is 1095,And the linear relationship was good(r=0 9998)In 20minutes,the dissolution rates were 80%.CONCLUSION The concentration of Norfloxacin can be detected by UV-spectrophotometry,it′s convient and rapid.It can also be wsed to detect the dvssolution of Norfloxacin capsule.

Wang Yanping, Liu Fuqiang, Wang Weidong, Liu Ge. Study on the method of dissolution test of norfloxacin Capsule[J]. Journal of Pharmaceutical Practice and Service, 1999, (4): 230-232.
Citation: Wang Yanping, Liu Fuqiang, Wang Weidong, Liu Ge. Study on the method of dissolution test of norfloxacin Capsule[J]. Journal of Pharmaceutical Practice and Service, 1999, (4): 230-232.
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