Intervention and prevention against irrational medication orders on antineoplastic drugs and total parenteral nutrition solution

ZHOU Jin; GE Jiyun; SUN Huihui; HUANG Mina; FU Zhenhe; HUANG Yufeng

doi:10.3969/j.issn.1006-0111.2017.05.023

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Objective To study the irrational intravenous (IV) medication orders and promote rational medication applications. Methods A retrospective analysis was conducted to analyze the irrational prescriptions from January to December 2016. Results Among 39 948 IV medication orders reviewed, there were 134 irrational prescriptions of cytotoxic drugs (0.33%) and 222 irrational prescriptions of total parenteral nutrition(TPN)(0.56%).Within 356 irrational prescriptions, 19 had improper amount of diluent(5.34%), 95 inappropriate dosage(26.69%), 12 drug incompatibility(3.37%), 8 wrong diluent (2.24%) and 222 inappropriate TPN orders (62.36%). Conclusion The interventions of the clinical pharmacists are needed to reduce medication errors and improve the drug safety and effectiveness.

Intervention and prevention against irrational medication orders on antineoplastic drugs and total parenteral nutrition solution

Department of Pharmacy, Eastern Hepatobiliary Surgery Hospital Affiliated to Second Military Medical University, Shanghai 200438, China

Received Date: 2017-05-19

Rev Recd Date: 2017-07-14

Key words:

pharmacy intravenous admixture service /
irrational prescriptions /
rational analysis

Abstract: Objective To study the irrational intravenous (IV) medication orders and promote rational medication applications. Methods A retrospective analysis was conducted to analyze the irrational prescriptions from January to December 2016. Results Among 39 948 IV medication orders reviewed, there were 134 irrational prescriptions of cytotoxic drugs (0.33%) and 222 irrational prescriptions of total parenteral nutrition(TPN)(0.56%).Within 356 irrational prescriptions, 19 had improper amount of diluent(5.34%), 95 inappropriate dosage(26.69%), 12 drug incompatibility(3.37%), 8 wrong diluent (2.24%) and 222 inappropriate TPN orders (62.36%). Conclusion The interventions of the clinical pharmacists are needed to reduce medication errors and improve the drug safety and effectiveness.

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Reference (8)

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Intervention and prevention against irrational medication orders on antineoplastic drugs and total parenteral nutrition solution

doi: 10.3969/j.issn.1006-0111.2017.05.023

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通讯作者: 陈斌, [email protected]

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