WANG Qiang, WANG Xiaohua. Three new triterpene glycosides from Stichopus variegatus[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(5): 431-436,454. doi: 10.3969/j.issn.1006-0111.2016.05.013
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WANG Qiang, WANG Xiaohua. Three new triterpene glycosides from Stichopus variegatus[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(5): 431-436,454. doi: 10.3969/j.issn.1006-0111.2016.05.013
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Three new triterpene glycosides from Stichopus variegatus
- Received Date: 2015-03-13
- Rev Recd Date:
2016-07-01
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Abstract
Objective To study the chemical constituents from the Stichopus variegatus. Method The compounds were isolated and purified by silica gel column chromatography, Sephadex LH-20 gel filtration and recrystallization. The structures of these compounds were identified through chemical reactions and spectral analyses, such as IR,1H,13C NMR,MS. Results Three compounds were identified as 3-O-[3-O-methyl-β-D-glucopyranosyl(1→3)-β-D-xylopyranosyl(1→3)-β-D-glucopyranosyl(1→2)-β-D-xylopyranosyl]-holosta-7,24-diene-3β,23S-diol, named as variegatuside C; 3-O-{3-O-methyl-β-D-glucopy-ranosyl(1→3)-β-D-xylopyranosyl(1→4)-β-D-glucopyranosyl(1→2)[β-D-glucopyranosyl(1→4)]-β-D-xylopyranosyl-holosta-8-ene-3β,23S-diol, named as variegatuside D; 3-O-{3-O-methyl-β-D-glucopyranosyl(1→3)-β-D-xylopyranosyl(1→4)-β-D-glucopyranosyl(1→2)[3-O-methyl-β-D-glucopyranosyl(1→3)-β-D-glucopyranosyl(1→4)]-β-D-xylopyranosyl｝-holosta-9-ene-3β,23S-diol, named as variegatuside E. Conclusion All three compounds are new compounds.
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