摘要:
目的 探讨胃舒乐颗粒联用雷贝拉唑治疗慢性胃病的有效性。 方法 选择488例慢性胃病患者分为治疗组与对照组。对照组:口服雷贝拉唑肠溶胶囊,1次/d,20 mg/次;治疗组:在对照组基础上加服胃舒乐颗粒,3次/d,10 g/次,3周为1个疗程。分别比较两组疾病疗效、内镜检查及中医证型疗效。 结果 功能消化不良及浅表性胃炎治疗组与对照组比较,疗效有统计学差异 (P<0.01);萎缩性胃炎治疗组与对照组比较,疗效有统计学差异(P<0.05);治疗组与对照组内镜检查病变疗效比较,具有统计学差异(P<0.05)。中医证型疗效中,肝胃湿热证、肝气犯胃证治疗组与对照组比较,疗效差异显著,有统计学意义(P<0.01),胃络瘀血证、脾胃虚寒证、寒热夹杂证治疗组与对照组比较,疗效有统计学差异(P<0.05)。 结论 胃舒乐颗粒联用雷贝拉唑治疗慢性胃病临床总有效率、治愈率较高,未见不良反应。
Abstract:
Objective To investigate the effectiveness of the Weishule granule therapy with rabeprazole particles associated chronic stomach. Methods 488 cases of chronic gastritis were divided into treatment group and control group. Control group: oral rabeprazole enteric-coated capsules, 1 time/d, 20 mg/times; treatment groups: on the basis of additional services Weishule granules, 3 times/d, 10 g/ times, three weeks for a course respectively.The efficacy of two diseases, endoscopy and TCM syndromes were compared. Results The treatment effect among functional dyspepsia, gastritis treatment group and the control group had statistically difference (P<0.01); The treatment effect between atrophic gastritis treatment group and the control group was statistically difference (P<0.05); The efficacy of endoscopic lesions between the treatment group and the control group was statistically difference (P<0.05). TCM syndrome, the liver and stomach damp-heat syndrome, Fan Wei qi syndrome treatment group and the control group, had statistically difference (P<0.01), stomach meridian blood stasis, spleen deficiency syndrome, cold and heat mixture syndrome treatment group and the control group had statistically difference(P<0.05). Conclusion The effective rate and cure rate of Weishule granule combined rabeprazole azole in patients with chronic stomach trouble was better with less adverse reactions.
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