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Volume 28 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(3): 213-214

WEI Jing-hai, WEI Jing-hai, WEI Jing-hai, WEI Jing-hai. Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 213-214.
Citation: WEI Jing-hai, WEI Jing-hai, WEI Jing-hai, WEI Jing-hai. Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 213-214.
shu

Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection

  • 1.

    Department of Pharmacy,Beijing Children's Hospital,Affiliated to Capital University of Medical Sciences,Beijing 100045,China

  • 2.

    Department of Pharmaceutical Analysis,Shenyang Pharmaceutical University,Shenyang 110016,China

  • Received Date: 2009-08-24
  • Rev Recd Date: 2009-11-03
  • Objective To study the stability of glucose and sodium potassium chloride injection(GNK) mixing with cefepime hydrochloride in room temperature. Methods RP-HPLC was applied to determine the content change of cefepime hydrochloride in different time.The pH,quantity of non-soluble particulate and appearance of mixtures were also observed. Results In room temperature the mixtures produced neither gas nor sediment.The pH,quantity of non-soluble particulate and content did not change within 8 hours. Conclusion The mixtures of GNK mixing with cefepime hydrochloride are stable in 8 hours.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection

  • 1. Department of Pharmacy,Beijing Children's Hospital,Affiliated to Capital University of Medical Sciences,Beijing 100045,China
  • 2. Department of Pharmaceutical Analysis,Shenyang Pharmaceutical University,Shenyang 110016,China
  • Received Date: 2009-08-24
  • Rev Recd Date: 2009-11-03

Abstract: Objective To study the stability of glucose and sodium potassium chloride injection(GNK) mixing with cefepime hydrochloride in room temperature. Methods RP-HPLC was applied to determine the content change of cefepime hydrochloride in different time.The pH,quantity of non-soluble particulate and appearance of mixtures were also observed. Results In room temperature the mixtures produced neither gas nor sediment.The pH,quantity of non-soluble particulate and content did not change within 8 hours. Conclusion The mixtures of GNK mixing with cefepime hydrochloride are stable in 8 hours.

WEI Jing-hai, WEI Jing-hai, WEI Jing-hai, WEI Jing-hai. Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 213-214.
Citation: WEI Jing-hai, WEI Jing-hai, WEI Jing-hai, WEI Jing-hai. Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 213-214.
shu

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