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Volume 28 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(3): 209-210,222

CAO Wen, XU Dao-long, LI Tie-jun. Optimization of extraction process of compound Shuiniujiao granule by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 209-210,222.
Citation: CAO Wen, XU Dao-long, LI Tie-jun. Optimization of extraction process of compound Shuiniujiao granule by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 209-210,222.
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Optimization of extraction process of compound Shuiniujiao granule by orthogonal test

  • 1.

    Chinese Medicine Hospital,Shanghai Putuo District,Shanghai,200062

  • 2.

    Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai,200433

  • Received Date: 2009-12-25
  • Rev Recd Date: 2010-05-14
  • Objective To select the best extraction process in preparation of compound Shuiniujiao granule. Methods The extraction solvent,add water,extraction times and extraction time as the study factors,each factor orthogonal design method developed three horizontal,and use the Results of the corresponding pharmacodynamic evaluation of the efficacy of each role in a process,combined with the yield and the actual production process to select the best. Results 50% ethanol,plus 8 times the amount of extracted three times,each time a small process when the compound derived from buffalo horn grain yield of preparation and pharmacodynamics of the most satisfactory Results. Conclusion Orthogonal design and the corresponding pharmacodynamic Results of the experiment to select the extraction process is a reasonable approach should be advocated.
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通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Optimization of extraction process of compound Shuiniujiao granule by orthogonal test

  • 1. Chinese Medicine Hospital,Shanghai Putuo District,Shanghai,200062
  • 2. Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai,200433
  • Received Date: 2009-12-25
  • Rev Recd Date: 2010-05-14

Abstract: Objective To select the best extraction process in preparation of compound Shuiniujiao granule. Methods The extraction solvent,add water,extraction times and extraction time as the study factors,each factor orthogonal design method developed three horizontal,and use the Results of the corresponding pharmacodynamic evaluation of the efficacy of each role in a process,combined with the yield and the actual production process to select the best. Results 50% ethanol,plus 8 times the amount of extracted three times,each time a small process when the compound derived from buffalo horn grain yield of preparation and pharmacodynamics of the most satisfactory Results. Conclusion Orthogonal design and the corresponding pharmacodynamic Results of the experiment to select the extraction process is a reasonable approach should be advocated.

CAO Wen, XU Dao-long, LI Tie-jun. Optimization of extraction process of compound Shuiniujiao granule by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 209-210,222.
Citation: CAO Wen, XU Dao-long, LI Tie-jun. Optimization of extraction process of compound Shuiniujiao granule by orthogonal test[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 209-210,222.
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