Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 28 Issue 3
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(3): 193-195

WU Xue-bin, YU Hui-hua, Tang Liang, YOU Ben-ming. Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 193-195.
Citation: WU Xue-bin, YU Hui-hua, Tang Liang, YOU Ben-ming. Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 193-195.
shu

Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule

  • 1.

    Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200433,China

  • 2.

    Shanghai Tianshili Pharmceutical Company Limited,Shanghai 201203,China

  • 3.

    Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China

  • Received Date: 2009-12-22
  • Rev Recd Date: 2010-04-08
  • Objective To study the anti-inflammatory and analgesic effects of Tongmaiyushang capsule. Methods Tumidness of small rat ears was induced by dimethylbenzene.Acute and chronic inflammation of rats were induced by carrageenin and tampon embedding respectively.The pain model was made by hot plate and writhing tests.Animals were divided into five groups: the blank control group;the positive control group;the low,middle and high dose of Tongmaiyushang capsule groups to investigate the anti-inflammatory and analgesic effect of the Tongmaiyushang capsule. Results The capillary permeability was decreased and the effusion of inflammatory mediator was reduced in small rat.Tumidness of small rat ears caused by dimethylbenzene and inflammation reaction induced by carrageenin were significantly inhibited with the reduction of leukocytes.The hyperplasia of granulation tissue in rats was also be inhibited.The capsule could improve the threshold of pain,prolong the incubation period of pain,decrease the quantity of body wrest of small rats.The analgesia rate of three groups was 49.6%,43.5%,33.3%,respectively. Conclusion Tongmaiyushang capsule has good anti-inflammatory and analgesic effects.
  • 加载中
通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2381) PDF downloads(369) Cited by()

Related
Proportional views

Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule

  • 1. Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200433,China
  • 2. Shanghai Tianshili Pharmceutical Company Limited,Shanghai 201203,China
  • 3. Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China
  • Received Date: 2009-12-22
  • Rev Recd Date: 2010-04-08

Abstract: Objective To study the anti-inflammatory and analgesic effects of Tongmaiyushang capsule. Methods Tumidness of small rat ears was induced by dimethylbenzene.Acute and chronic inflammation of rats were induced by carrageenin and tampon embedding respectively.The pain model was made by hot plate and writhing tests.Animals were divided into five groups: the blank control group;the positive control group;the low,middle and high dose of Tongmaiyushang capsule groups to investigate the anti-inflammatory and analgesic effect of the Tongmaiyushang capsule. Results The capillary permeability was decreased and the effusion of inflammatory mediator was reduced in small rat.Tumidness of small rat ears caused by dimethylbenzene and inflammation reaction induced by carrageenin were significantly inhibited with the reduction of leukocytes.The hyperplasia of granulation tissue in rats was also be inhibited.The capsule could improve the threshold of pain,prolong the incubation period of pain,decrease the quantity of body wrest of small rats.The analgesia rate of three groups was 49.6%,43.5%,33.3%,respectively. Conclusion Tongmaiyushang capsule has good anti-inflammatory and analgesic effects.

WU Xue-bin, YU Hui-hua, Tang Liang, YOU Ben-ming. Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 193-195.
Citation: WU Xue-bin, YU Hui-hua, Tang Liang, YOU Ben-ming. Experimental studies on anti-inflammatory and analgesic action of the Tongmaiyushang capsule[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 193-195.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: [email protected]

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return