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Volume 27 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2009  >  27(3): 177-178,188

TIAN Jin, LU Jian, YANG Ji-shun, HU Jin-hong. Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 177-178,188.
Citation: TIAN Jin, LU Jian, YANG Ji-shun, HU Jin-hong. Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 177-178,188.
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Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts

  • 1.

    Graduates Management Brigade of SMMU, Shanghai 200433 China

  • 2.

    Department of Pharmacy, Changhai Hospital, Shanghai 200433, China

  • Received Date: 2009-03-18
  • Objective :To explore the rule of secretion of IL-10 stimulated sulfur mustard in human fibroblasts. Methods :The ELISA was used to detect the relationship between dose and efficacy,time course and efficacy of which sulfur mustard adjusted the secretion of IL-10. Results :A portion of IL-10 could be secreted by the human fibroblasts.The secretion of IL-10 could be significantly stimulated after the function of sulfur mustard which depended on the time-course and dosage. Conclusion :The therapeutic mechanism of sulfur mustard to Psoriasis might related with the promotion of the secretion of IL-10.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts

  • 1. Graduates Management Brigade of SMMU, Shanghai 200433 China
  • 2. Department of Pharmacy, Changhai Hospital, Shanghai 200433, China
  • Received Date: 2009-03-18

Abstract: Objective :To explore the rule of secretion of IL-10 stimulated sulfur mustard in human fibroblasts. Methods :The ELISA was used to detect the relationship between dose and efficacy,time course and efficacy of which sulfur mustard adjusted the secretion of IL-10. Results :A portion of IL-10 could be secreted by the human fibroblasts.The secretion of IL-10 could be significantly stimulated after the function of sulfur mustard which depended on the time-course and dosage. Conclusion :The therapeutic mechanism of sulfur mustard to Psoriasis might related with the promotion of the secretion of IL-10.

TIAN Jin, LU Jian, YANG Ji-shun, HU Jin-hong. Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 177-178,188.
Citation: TIAN Jin, LU Jian, YANG Ji-shun, HU Jin-hong. Study on secretion of IL-10 stimulated by sulfur mustard in Human fibroblasts[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(3): 177-178,188.
shu

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