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Volume 26 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (1): 43-45

LIU Qiu-ru, MA Ai-ying, SHEN Jie. Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 43-45.
Citation: LIU Qiu-ru, MA Ai-ying, SHEN Jie. Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 43-45.
shu

Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)

  • The 455th Hospital of PLA, Shanghai 200052,China

  • Received Date: 2007-04-16
  • Rev Recd Date: 2006-10-30
  • Objective: To compare the prophylactic efficacy of ondansetron,granisetron,and tropisetron on vomiting caused by TACE. Methods: 120 patients(with primary hepatocellular carcinoma) were randomly divided into four groups to receive ondanstron,granisetron,tropisetron via liver artery injection (n=30) and combined with metoclopramide as controls (n=30).The antiemetic efficacies were compared among the four groups for 5 consecutive days after TACE. Results: The effective rate of tropisetron group was significantly higher than that of the control group (P<0.05). Conclusion: Tropisetron is an effective antiemetic drug in controlling vomiting caused by TACE and should be advocated in clinical practice.
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通讯作者: 陈斌, [email protected]
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Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)

  • The 455th Hospital of PLA, Shanghai 200052,China
  • Received Date: 2007-04-16
  • Rev Recd Date: 2006-10-30

Abstract: Objective: To compare the prophylactic efficacy of ondansetron,granisetron,and tropisetron on vomiting caused by TACE. Methods: 120 patients(with primary hepatocellular carcinoma) were randomly divided into four groups to receive ondanstron,granisetron,tropisetron via liver artery injection (n=30) and combined with metoclopramide as controls (n=30).The antiemetic efficacies were compared among the four groups for 5 consecutive days after TACE. Results: The effective rate of tropisetron group was significantly higher than that of the control group (P<0.05). Conclusion: Tropisetron is an effective antiemetic drug in controlling vomiting caused by TACE and should be advocated in clinical practice.

LIU Qiu-ru, MA Ai-ying, SHEN Jie. Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 43-45.
Citation: LIU Qiu-ru, MA Ai-ying, SHEN Jie. Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 43-45.
shu

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