Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 25 Issue 2
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2007  >  (2): 100-101

LI Qi, WANG Feng-shan, LING Pei-xue, ZHANG Tian-min. Influence of sodium hyaluronate as vehicle on chloramphenicol release in eye drops[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 100-101.
Citation: LI Qi, WANG Feng-shan, LING Pei-xue, ZHANG Tian-min. Influence of sodium hyaluronate as vehicle on chloramphenicol release in eye drops[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 100-101.
shu

Influence of sodium hyaluronate as vehicle on chloramphenicol release in eye drops

  • 1.

    Pharmacy School of Shandong University,Jinan 250012,China;Department of Pharmacy,The Chest Hospital of Shandong Province,Jinan 250013,China

  • 2.

    Pharmacy School of Shandong University,Jinan 250012,China

  • Received Date: 2006-04-14
  • Objective: To study the influence factores of chloramphenicol release with sodium hyaluronate as vehicle in eye drops. Methods: The penetration rates of chloramphenicol were determined with modified Franz diffusion cell in solutions with different influ-ence factores. Results: The increase of solution viscosity could decrease the release rate of chloramphenicol.The release rates of chlor-amphenicol decreased with the concentrations of sodium hyaluronate increased and increased with the concentrations of chloramphenicol increased. Conclusion: The release rate of chloramphenicol in eye drops is concerned with viscosity of solution and drug concentration, but there is a limite to the drug sustained release by increasing viscosity of solution.
  • 加载中
通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2129) PDF downloads(702) Cited by()

Related
Proportional views

Influence of sodium hyaluronate as vehicle on chloramphenicol release in eye drops

  • 1. Pharmacy School of Shandong University,Jinan 250012,China;Department of Pharmacy,The Chest Hospital of Shandong Province,Jinan 250013,China
  • 2. Pharmacy School of Shandong University,Jinan 250012,China
  • Received Date: 2006-04-14

Abstract: Objective: To study the influence factores of chloramphenicol release with sodium hyaluronate as vehicle in eye drops. Methods: The penetration rates of chloramphenicol were determined with modified Franz diffusion cell in solutions with different influ-ence factores. Results: The increase of solution viscosity could decrease the release rate of chloramphenicol.The release rates of chlor-amphenicol decreased with the concentrations of sodium hyaluronate increased and increased with the concentrations of chloramphenicol increased. Conclusion: The release rate of chloramphenicol in eye drops is concerned with viscosity of solution and drug concentration, but there is a limite to the drug sustained release by increasing viscosity of solution.

LI Qi, WANG Feng-shan, LING Pei-xue, ZHANG Tian-min. Influence of sodium hyaluronate as vehicle on chloramphenicol release in eye drops[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 100-101.
Citation: LI Qi, WANG Feng-shan, LING Pei-xue, ZHANG Tian-min. Influence of sodium hyaluronate as vehicle on chloramphenicol release in eye drops[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 100-101.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: [email protected]

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return