Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 25 Issue 2
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2007  >  (2): 85-87

LIN Huan-bing, ZHONG Wen, LI Tie-jun, RUI Yao-cheng, XU Jiang-Ping, ZHANG Wei-Dong. Influence of Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobarbital sodium in mice[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 85-87.
Citation: LIN Huan-bing, ZHONG Wen, LI Tie-jun, RUI Yao-cheng, XU Jiang-Ping, ZHANG Wei-Dong. Influence of Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobarbital sodium in mice[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 85-87.
shu

Influence of Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobarbital sodium in mice

  • 1.

    Department of Pharmacology,Southern Medical University,Guangzhou 510515,China

  • 2.

    Department of HBO,No.422 Hospital of PLA,Zhanjiang 534005,China

  • 3.

    School of Pharmacy,Second Military Medical University,Shanghai 200433,China

  • Received Date: 2006-12-25
  • Objective: To survey the influence of the Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobar-bital sodium in mice. Methods: ICR mice were randomly divided into 4 equal groups(Dengzhanxixin injection group,breviscapine group,naloxone hydrochloride group and sodium chloride group),effects of drug on mice hypnosis induced by pentoharbital sodium in suprathreshold dose or hypnotic dose was observed.Effects of drugs on mice spontaneous movement and equilibrium function was also observed. Results: Comparing with the group of sodium chloride,the group of Dengzhanxixin injection,breviscapine and naloxone hydrochloride significantly prolonged the time of falling asleep,shorted the duration of hypnosis induced by pentobarbital sodium in su-prathreshold dose in mice respectively(P＜0.05),shorted vanishing period of righting reflex in the mice induced by pentobarbital sodi-um in hypnotic dose(P＜0.05 ). Conclusion: Dengzhanxixin injection and breviscapine had arousal effects on pentobarbital sodium treated mice.
  • 加载中
通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2475) PDF downloads(459) Cited by()

Related
Proportional views

Influence of Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobarbital sodium in mice

  • 1. Department of Pharmacology,Southern Medical University,Guangzhou 510515,China
  • 2. Department of HBO,No.422 Hospital of PLA,Zhanjiang 534005,China
  • 3. School of Pharmacy,Second Military Medical University,Shanghai 200433,China
  • Received Date: 2006-12-25

Abstract: Objective: To survey the influence of the Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobar-bital sodium in mice. Methods: ICR mice were randomly divided into 4 equal groups(Dengzhanxixin injection group,breviscapine group,naloxone hydrochloride group and sodium chloride group),effects of drug on mice hypnosis induced by pentoharbital sodium in suprathreshold dose or hypnotic dose was observed.Effects of drugs on mice spontaneous movement and equilibrium function was also observed. Results: Comparing with the group of sodium chloride,the group of Dengzhanxixin injection,breviscapine and naloxone hydrochloride significantly prolonged the time of falling asleep,shorted the duration of hypnosis induced by pentobarbital sodium in su-prathreshold dose in mice respectively(P＜0.05),shorted vanishing period of righting reflex in the mice induced by pentobarbital sodi-um in hypnotic dose(P＜0.05 ). Conclusion: Dengzhanxixin injection and breviscapine had arousal effects on pentobarbital sodium treated mice.

LIN Huan-bing, ZHONG Wen, LI Tie-jun, RUI Yao-cheng, XU Jiang-Ping, ZHANG Wei-Dong. Influence of Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobarbital sodium in mice[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 85-87.
Citation: LIN Huan-bing, ZHONG Wen, LI Tie-jun, RUI Yao-cheng, XU Jiang-Ping, ZHANG Wei-Dong. Influence of Dengzhanxixin injection and breviscapine on the hypnotic effects of pentobarbital sodium in mice[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 85-87.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: [email protected]

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return