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Volume 24 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2006  >  (2): 81-83

JIANG Tao, QIN Lu-ping, ZHENG Han-chen, HAN Ting. Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 81-83.
Citation: JIANG Tao, QIN Lu-ping, ZHENG Han-chen, HAN Ting. Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 81-83.
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Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats

  • 1.

    Department of Pharmacogonosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China; Shanghai Nabio Biotechnology Co., Ltd.Shanghai 201203, China

  • 2.

    Department of Pharmacogonosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2005-10-27
  • Objective : To study the effects of Qingzhiyuan soft capsule(QZY)on blood lipid and antioxidant activity in hyperlipi-demia rats. Methods : Fifty Wister rats were randomly divided into five groups according to body weight and serum cholesterol levels.They were fed one of five diets, a reference diet, a high fat supplemented diet and a high fat supplemented with 20mg/kg, 5mg/kg QZY, a positive diets.After three weeks, blood lipid and antioxidant activity were determined respectively. Results : Compared with model, QZY could reduced the serum TC, TG, LDL-C concentration, increased SOD and GSH-Px activities, decreased MDA level significantly(P<0.05). Conclusion : QZY might play an important role in preventing hyperlipidemia through its antioxidative effect.
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通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats

  • 1. Department of Pharmacogonosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China; Shanghai Nabio Biotechnology Co., Ltd.Shanghai 201203, China
  • 2. Department of Pharmacogonosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2005-10-27

Abstract: Objective : To study the effects of Qingzhiyuan soft capsule(QZY)on blood lipid and antioxidant activity in hyperlipi-demia rats. Methods : Fifty Wister rats were randomly divided into five groups according to body weight and serum cholesterol levels.They were fed one of five diets, a reference diet, a high fat supplemented diet and a high fat supplemented with 20mg/kg, 5mg/kg QZY, a positive diets.After three weeks, blood lipid and antioxidant activity were determined respectively. Results : Compared with model, QZY could reduced the serum TC, TG, LDL-C concentration, increased SOD and GSH-Px activities, decreased MDA level significantly(P<0.05). Conclusion : QZY might play an important role in preventing hyperlipidemia through its antioxidative effect.

JIANG Tao, QIN Lu-ping, ZHENG Han-chen, HAN Ting. Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 81-83.
Citation: JIANG Tao, QIN Lu-ping, ZHENG Han-chen, HAN Ting. Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats[J]. Journal of Pharmaceutical Practice and Service, 2006, (2): 81-83.
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