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Volume 23 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2005  >  (5): 306-308

YUAN Qing-Hua, SUN Shu-lian, RUI jing, HUA Xiao-dong. Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique[J]. Journal of Pharmaceutical Practice and Service, 2005, (5): 306-308.
Citation: YUAN Qing-Hua, SUN Shu-lian, RUI jing, HUA Xiao-dong. Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique[J]. Journal of Pharmaceutical Practice and Service, 2005, (5): 306-308.
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Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique

  • Tianjin Institute for Drug Control, Tianjin 300070, China

  • Received Date: 2004-12-05
  • Objective To Establish the kinetre-turbidimetrie techmque for practical quahly control on endotoxin content in elmda invcin hydrochloride mjection Methods The kmetie-turbidimetrie techmque and ehminated interfere factors approved by Chinese pharmacopoeia 2000 edition were used. Results Endotoxin added to clindamyem hydrochloride mjection was recovered in a quantitative manner showing neither inhibition nor enhancement in diluted solution concentration 0.075 mg/mL, the endotoxin recovery was more than 50 percent and less than 200 percent. Conclusion These results suggested that the kinetre-turbidimetrie technique of LAL-test was suitable for the detection of eudoloxin in elindamycin hydrochloride mjection.
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Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique

  • Tianjin Institute for Drug Control, Tianjin 300070, China
  • Received Date: 2004-12-05

Abstract: Objective To Establish the kinetre-turbidimetrie techmque for practical quahly control on endotoxin content in elmda invcin hydrochloride mjection Methods The kmetie-turbidimetrie techmque and ehminated interfere factors approved by Chinese pharmacopoeia 2000 edition were used. Results Endotoxin added to clindamyem hydrochloride mjection was recovered in a quantitative manner showing neither inhibition nor enhancement in diluted solution concentration 0.075 mg/mL, the endotoxin recovery was more than 50 percent and less than 200 percent. Conclusion These results suggested that the kinetre-turbidimetrie technique of LAL-test was suitable for the detection of eudoloxin in elindamycin hydrochloride mjection.

YUAN Qing-Hua, SUN Shu-lian, RUI jing, HUA Xiao-dong. Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique[J]. Journal of Pharmaceutical Practice and Service, 2005, (5): 306-308.
Citation: YUAN Qing-Hua, SUN Shu-lian, RUI jing, HUA Xiao-dong. Measurement of endotoxin in clindamycin hydrochloride injection by the kineticturbidimetric technique[J]. Journal of Pharmaceutical Practice and Service, 2005, (5): 306-308.
shu

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