Determination of content in aripirazole tablets by HPLC

CHENG Yirig; PU Cun-hai; WU Ai-lan; WANG Bo

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Volume 23 Issue 5

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2005 > (5): 297-299

CHENG Yirig, PU Cun-hai, WU Ai-lan, WANG Bo. Determination of content in aripirazole tablets by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2005, (5): 297-299.

Citation:

CHENG Yirig, PU Cun-hai, WU Ai-lan, WANG Bo. Determination of content in aripirazole tablets by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2005, (5): 297-299.

Determination of content in aripirazole tablets by HPLC

1.
Jiangsu Institute for Drug Control, Nanjing 210008, China
2.
Zhongshan Pharmaceutical Factory, Nanjing 210012, China

Received Date: 2005-06-12

Abstract

Objective To established a HPLC method for the determination of alipaizuo in its tablets. Method Alipaizuo can be separated on column with a mixture of 0.02% phosphoric acid(pH=3.0, adjusted with triethylamine) and acetonitrile (46:54) as mobile phase and detected at 254 nm. Result The linear range was from 2.088μg/mL to 66. 816μg/mL (r=0.99999) for alipaizuo. The average recovery was 99.39%. Conclusion The method is simple, rapid, accurate and reliable.
- HPLC,
- alipaizuo
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通讯作者: 陈斌, [email protected]

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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