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Volume 22 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2004  >  (5): 278-280

WANG Jin, ZHANG Zhi-guo. Antitussive, expectorant and antiasthmatic actions of Qiguanyan pill[J]. Journal of Pharmaceutical Practice and Service, 2004, (5): 278-280.
Citation: WANG Jin, ZHANG Zhi-guo. Antitussive, expectorant and antiasthmatic actions of Qiguanyan pill[J]. Journal of Pharmaceutical Practice and Service, 2004, (5): 278-280.
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Antitussive, expectorant and antiasthmatic actions of Qiguanyan pill

  • Institute for Drug and Instrument Control, Shenyang Military Command of PLA, Shenyang 110026, China

  • Received Date: 2004-03-05
  • Objective To study antitussive, expectorant and antiasthmatic actions of Qiguanye pill. Methods Histamine was used to induce tracheaspasm in whole body and Guinea pig's isolated trachea test was used to observe the antiasthmatic action Of Qiguanye pill. Phenol red test was used to observe its expectorant action in mice. The cough of animal was induced by ammonia water to trachea tract. Results Qiguanye pill could obviously prolong the incubation period of asthma produced by histamine and also could markedly reduce the contraction amplitude, induced by histamine and acetylcholine of isolated trachea of Guinea pig. The contraction amplitudes were reduced. It could markedly increase excretion of phenol red in the trachial cavity of mice and could obviously reduce cough times of felines and mice. Conclusion Qiguanye pill has good antitussive,expectorant and antiasthmatic actions.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Antitussive, expectorant and antiasthmatic actions of Qiguanyan pill

  • Institute for Drug and Instrument Control, Shenyang Military Command of PLA, Shenyang 110026, China
  • Received Date: 2004-03-05

Abstract: Objective To study antitussive, expectorant and antiasthmatic actions of Qiguanye pill. Methods Histamine was used to induce tracheaspasm in whole body and Guinea pig's isolated trachea test was used to observe the antiasthmatic action Of Qiguanye pill. Phenol red test was used to observe its expectorant action in mice. The cough of animal was induced by ammonia water to trachea tract. Results Qiguanye pill could obviously prolong the incubation period of asthma produced by histamine and also could markedly reduce the contraction amplitude, induced by histamine and acetylcholine of isolated trachea of Guinea pig. The contraction amplitudes were reduced. It could markedly increase excretion of phenol red in the trachial cavity of mice and could obviously reduce cough times of felines and mice. Conclusion Qiguanye pill has good antitussive,expectorant and antiasthmatic actions.

WANG Jin, ZHANG Zhi-guo. Antitussive, expectorant and antiasthmatic actions of Qiguanyan pill[J]. Journal of Pharmaceutical Practice and Service, 2004, (5): 278-280.
Citation: WANG Jin, ZHANG Zhi-guo. Antitussive, expectorant and antiasthmatic actions of Qiguanyan pill[J]. Journal of Pharmaceutical Practice and Service, 2004, (5): 278-280.
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