Analysis of stenotrophomonas maltoppilia's drug resistance

Key words: 
• stenotrophomonas maltophilia /
• extra-pumping system /
• multi-drug resistance

Abstract: Objective To analyse the drug resistance of the stenotrophomonas maltophilia in order to guide rational drug using in clinical. Methods The automatic drug sensitive test and method that the paper spreads medicine sensitive test were carried on to 101 stems of the stenotrophomonas maltophilia with the index of the VITEK system, and drug sensitive test with long-term difficult to treat nature's stenotrophomonas maltophilia infection patient was carried once a week. Results In all clinical samples,stenotrophomonas maltophilia separated from phlegm liquid is the most (75%), then is the clear urine(10%),this fungus is nature resistance to the action of the iminepinan. The drug resistance of ampicillin,amoxicillin/clavulanic acid,cefazolin,furantoin,cefuroxime are 100%. Amika-cin, aztreonam, cefmetazole, ceftriaxone, cefotaxime, gentamicin's sensitive rate are under 20%, for levofloxacin, Compound sinomin, ceftazidime,cefoperazone/sulbactam,the drug resistance is 18.92%,22.86%,13.95%,2.50% respectively. Conclusion Stenotrophomonas maltophilia is the important pathogen fungus that infects in hospital, and resistance to most of the antibiotics, Cefoperazone/sul-bactam is the first-selected medicine for it; Stenotrophomonas maltophilia is easy to produce medicament inductivity resistance to a few sensitive drugs.