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Volume 19 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2001  >  (6): 346-349,345

XUE Xin, ZOU Hao, LIU Chao-mei, JIANG Xue-tao. Preparation of fluconazole sustained release tablets and study on the release in vitro[J]. Journal of Pharmaceutical Practice and Service, 2001, (6): 346-349,345.
Citation: XUE Xin, ZOU Hao, LIU Chao-mei, JIANG Xue-tao. Preparation of fluconazole sustained release tablets and study on the release in vitro[J]. Journal of Pharmaceutical Practice and Service, 2001, (6): 346-349,345.
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Preparation of fluconazole sustained release tablets and study on the release in vitro

  • 1.

    Department of Pharmacy, 31 Hospital of PLA, Baoji 223001, China

  • 2.

    Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2001-07-03
  • OBJECTIVE To prepare fluconazole sustained release tablets for the use of vagina.METHODS The release rate was used to evaluate the formulation of the core tablet by orthogonal design. The tableting pressure and rate of dissolution rotation paddle were investigated for the effect on the sustained tablet.RESULTS FCZ 50mg,Carbopol 100mg,MCC 150mg,HPMC 90mg and starch 210mg would produce desirable sustained tablet.CONCLUSION Fluconazole sustained release tablets can be prepared for mycotic infection in vagina.
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通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Preparation of fluconazole sustained release tablets and study on the release in vitro

  • 1. Department of Pharmacy, 31 Hospital of PLA, Baoji 223001, China
  • 2. Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2001-07-03

Abstract: OBJECTIVE To prepare fluconazole sustained release tablets for the use of vagina.METHODS The release rate was used to evaluate the formulation of the core tablet by orthogonal design. The tableting pressure and rate of dissolution rotation paddle were investigated for the effect on the sustained tablet.RESULTS FCZ 50mg,Carbopol 100mg,MCC 150mg,HPMC 90mg and starch 210mg would produce desirable sustained tablet.CONCLUSION Fluconazole sustained release tablets can be prepared for mycotic infection in vagina.

XUE Xin, ZOU Hao, LIU Chao-mei, JIANG Xue-tao. Preparation of fluconazole sustained release tablets and study on the release in vitro[J]. Journal of Pharmaceutical Practice and Service, 2001, (6): 346-349,345.
Citation: XUE Xin, ZOU Hao, LIU Chao-mei, JIANG Xue-tao. Preparation of fluconazole sustained release tablets and study on the release in vitro[J]. Journal of Pharmaceutical Practice and Service, 2001, (6): 346-349,345.
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