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Volume 19 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2001  >  (3): 160-162

SU Kai-zhong, WEI Wen-shu, WEI Wei-ming, JIA Jin-huan, OU-YANG Ai-jun. Study on preclinical pharmacodynamics of San-he-wei-yao[J]. Journal of Pharmaceutical Practice and Service, 2001, (3): 160-162.
Citation: SU Kai-zhong, WEI Wen-shu, WEI Wei-ming, JIA Jin-huan, OU-YANG Ai-jun. Study on preclinical pharmacodynamics of San-he-wei-yao[J]. Journal of Pharmaceutical Practice and Service, 2001, (3): 160-162.
shu

Study on preclinical pharmacodynamics of San-he-wei-yao

  • 1.

    Dept of Pharmacology, Fuzhou Marine Bioengineering Research &, Development Center, Fuzhou 350026, China

  • 2.

    Fuzhou Medical College of PLA, Fuzhou 350003, China

  • 3.

    Second Military Medical University, Shang hai 200433, China

  • Received Date: 2000-12-11
  • OBJECTIVE To study the effects of San-he-wei-yao on gastric ulcer in mice and rats. METHODS The models of gastric ulcer were induced by restraint plus water-immersion,reserpine in mice and by pylorus ligation and acetic acid in rats respectively.San-he-wei-yao was given before or after gastric ulcer induction.RESULTS San-he-wei-yao inhibited dose-dependently development of the ulcers.The ulcer size,gastricacid production and pepsin activity were signif icantly decreased by both San-he-wei-yao and cimet idine.CONCLUSION San-he-wei-yao possesses ideal effects on gastric ulcer models.
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通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on preclinical pharmacodynamics of San-he-wei-yao

  • 1. Dept of Pharmacology, Fuzhou Marine Bioengineering Research &, Development Center, Fuzhou 350026, China
  • 2. Fuzhou Medical College of PLA, Fuzhou 350003, China
  • 3. Second Military Medical University, Shang hai 200433, China
  • Received Date: 2000-12-11

Abstract: OBJECTIVE To study the effects of San-he-wei-yao on gastric ulcer in mice and rats. METHODS The models of gastric ulcer were induced by restraint plus water-immersion,reserpine in mice and by pylorus ligation and acetic acid in rats respectively.San-he-wei-yao was given before or after gastric ulcer induction.RESULTS San-he-wei-yao inhibited dose-dependently development of the ulcers.The ulcer size,gastricacid production and pepsin activity were signif icantly decreased by both San-he-wei-yao and cimet idine.CONCLUSION San-he-wei-yao possesses ideal effects on gastric ulcer models.

SU Kai-zhong, WEI Wen-shu, WEI Wei-ming, JIA Jin-huan, OU-YANG Ai-jun. Study on preclinical pharmacodynamics of San-he-wei-yao[J]. Journal of Pharmaceutical Practice and Service, 2001, (3): 160-162.
Citation: SU Kai-zhong, WEI Wen-shu, WEI Wei-ming, JIA Jin-huan, OU-YANG Ai-jun. Study on preclinical pharmacodynamics of San-he-wei-yao[J]. Journal of Pharmaceutical Practice and Service, 2001, (3): 160-162.
shu

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