Investigation on the dissolution rate of nimodipine table in vetro

Key words: 
• UV spectrophotometry /
• nimodipine table /
• dissolution rate

Abstract: The dissolution rates of nimodipine table form three domestic pharmaceutical facto ries and abroad were determined with UV spectrophotomety. 30% alcohol solution was used as dissolvent.Data of experiments were conducted by computer and the parameters of dissolution rate(τ、t₀、m、T₅₀、Td、T₉₀)were treated with analysis of variance. The disolution rates of nimodip ine table for these 4 factories differed each other significantly(P<0.01). The result shows that the dissolution rates of nimodipine table form domestic pharmaceutical factories are not lower that from abroad.