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GAO Zhan, JING Changfeng. Analysis of the causes of gynecomastia in a male patient with heart failure by clinical pharmacist[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(5): 470-472. doi: 10.3969/j.issn.1006-0111.2019.05.017
Citation: GAO Zhan, JING Changfeng. Analysis of the causes of gynecomastia in a male patient with heart failure by clinical pharmacist[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(5): 470-472. doi: 10.3969/j.issn.1006-0111.2019.05.017

Analysis of the causes of gynecomastia in a male patient with heart failure by clinical pharmacist

doi: 10.3969/j.issn.1006-0111.2019.05.017
  • Received Date: 2019-04-12
  • Rev Recd Date: 2019-07-05
  • Objective To analyze the reason of gynecomastia in a male patient with heart failure and provide safer references for clinical prescriptions. Methods The patient's clinical symptoms,signs and laboratory findings in great detail were learned and the analysis and advice of treatment regimens were given by the clinical pharmacist learned individually. Results Gynecomastia was possible from the result of drugs,the reduction of the dose of the suspicious drug spironolactone and were put forward and adopted. Conclusions As for gynecomastia appeared in the drug treatment process,the clinical pharmacist could analyze and sort out suspicious drugs,then reflect to the prescriber.
  • [1] BRAUNSTEIN G D. Clinical practice. gynecomastia[J]. N Engl J Med, 2007, 357(12):1229-1237.
    [2] SINCLAIR M, GROSSMANN M, GOW P J, et al. Testosterone in men with advanced liver disease:abnormalities and implications[J]. J Gastroenterol Hepatol, 2015, 30(2):244-251.
    [3] 汪维艳, 杨京, 陆爽, 等. 男性肝硬化患者乳腺发育症与血清性激素及肝功能的相关性[J]. 中华消化杂志, 2015, 35(11):734-738.
    [4] 李碧虹, 陈君远, 吴毅丹, 等. 奥美拉唑67例不良反应分析[J]. 中国现代药物应用, 2009, 3(24):32-33.
    [5] 刘丽华. 头孢匹胺钠与奥美拉唑合用致男性乳腺增生症5例[J]. 临床合理用药杂志, 2009, 2(2):33.
    [6] CARVAJAL A, MACIAS D, GUTIÉRREZ A, et al. Gynaecomastia associated with proton pump inhibitors:a case series from the Spanish Pharmacovigilance System[J]. Drug Saf, 2007, 30(6):527-531.
    [7] 杨国亮, 王侠生. 现代皮肤病学[M]. 上海:上海医科大学出版社, 1996.
    [8] PITT B, ZANNAD F, REMME W J, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators[J]. N Engl J Med, 1999, 341(10):709-717.
    [9] CHAPMAN N, DOBSON J, WILSON S, et al. Effect of spironolactone on blood pressure in subjects with resistant hypertension[J]. Hypertension, 2007, 49(4):839-845.
    [10] FUKUI H, SAITO H, UENO Y, et al. Evidence-based clinical practice guidelines for liver cirrhosis 2015[J]. J Gastroenterol, 2016, 51(7):629-650.
    [11] ANGELI P, PRIA M D, DE BEI E, et al. Randomized clinical study of the efficacy of amiloride and potassium canrenoate in nonazotemic cirrhotic patients with ascites[J]. Hepatology, 1994, 19(1):72-79.
    [12] PITT B, REMME W, ZANNAD F, et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction[J]. N Engl J Med, 2003, 348(14):1309-1321.
    [13] 中华医学会心血管病学分会心力衰竭学组, 中国医师协会心力衰竭专业委员会中华心血管病杂志编辑委员会. 中国心力衰竭诊断和治疗指南2018[J]. 中华心血管病杂志, 2018, 46(10):760-789.
    [14] SWEETMAN S C. 马丁代尔药物大典[M]. 37版,北京:化学工业出版社, 2014.
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Analysis of the causes of gynecomastia in a male patient with heart failure by clinical pharmacist

doi: 10.3969/j.issn.1006-0111.2019.05.017

Abstract: Objective To analyze the reason of gynecomastia in a male patient with heart failure and provide safer references for clinical prescriptions. Methods The patient's clinical symptoms,signs and laboratory findings in great detail were learned and the analysis and advice of treatment regimens were given by the clinical pharmacist learned individually. Results Gynecomastia was possible from the result of drugs,the reduction of the dose of the suspicious drug spironolactone and were put forward and adopted. Conclusions As for gynecomastia appeared in the drug treatment process,the clinical pharmacist could analyze and sort out suspicious drugs,then reflect to the prescriber.

GAO Zhan, JING Changfeng. Analysis of the causes of gynecomastia in a male patient with heart failure by clinical pharmacist[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(5): 470-472. doi: 10.3969/j.issn.1006-0111.2019.05.017
Citation: GAO Zhan, JING Changfeng. Analysis of the causes of gynecomastia in a male patient with heart failure by clinical pharmacist[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(5): 470-472. doi: 10.3969/j.issn.1006-0111.2019.05.017
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