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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2018  >  36(6): 481-483,492

WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
Citation: WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
shu

Study on animal models and mechanisms of systemic lupus erythematosus

doi: 10.3969/j.issn.1006-0111.2018.06.001
  • 1.

    Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • 2.

    Department of Pharmacy, Shanghai Traditional Chinese Medicine Hospital, Shanghai 200071, China

  • 3.

    Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Shanghai TCM-Integrated Hospital Shanghai TCM-Integrated Research Institute of pulse tube disease, Shanghai 200082, China

  • Received Date: 2018-03-19
  • Rev Recd Date: 2018-09-12
  • Objective Systemic lupus erythematosus (SLE) models were mainly divided into spontaneous and induced models. Through the literature,spontaneous and induced SLE models and their main characteristics were reviewed, which provided references for the researchers to choose appropriate models for studying specific pathogenic mechanism and diagnostic criteria, searching for targeted treatment interventions and developing potential therapeutic drugs.
  • [1] WANG Z, XIE JY, XU H, et al. Effect of Matteuccia struthiopteris polysaccharides on systemic lupus erythematosus-like syndrome induced by Campylobacter jejuni in BALB/c mice[J]. Acta pharmaceutica Sinica, 2010, 45(6):711-717.
    [2] MOK CC, LAU CS. Pathogenesis of systemic lupus erythematosus[J]. J Clin Pathol, 2003, 56(7):481-490.
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    [9] MCPHEE CG, BUBIER JA, SPROULE TJ, et al. IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice[J]. J Immunol, 2013, 191(9):4581-4588.
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    [14] 吴言为.青蒿素衍生物SM934对系统性红斑狼疮的疗效及作用机制研究[D].2016:11-12.
    [15] LI H, ZHANG YY, SUN YN, et al. Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin[J]. Acta Pharmacol Sin, 2004, 25(6):807-811.
    [16] 力弘,章蕴毅,黄曦益,等.小鼠系统性红斑狼疮样综合征的诱导及病变特征[J].中国新药与临床杂志,2004,23(8):480-484.
    [17] ZHONG SP,WEN BG,HE KL.Chemical and physical nature ofactiveehrematin in SRS-lymphomamouse lymphocyte[J].Chin J Pathophysiol,1994,10(4):378-382.
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    [21] WANG Z, LI H, XU H,et al. Beneficial effect of Bupleurum polysaccharides on autoimmune disease induced by Campylobacter jejuni in BALB/c mice[J]. J Ethnopharmacol, 2009, 124(3):481-487.
    [22] 王铮,谢俊云,徐晗,等.贯众总多糖对空肠弯曲杆菌诱导的系统性红斑狼疮样综合征小鼠的作用[J].药学学报,2010,45(6):711-717.
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Study on animal models and mechanisms of systemic lupus erythematosus

doi: 10.3969/j.issn.1006-0111.2018.06.001
  • 1. Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • 2. Department of Pharmacy, Shanghai Traditional Chinese Medicine Hospital, Shanghai 200071, China
  • 3. Center for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Shanghai TCM-Integrated Hospital Shanghai TCM-Integrated Research Institute of pulse tube disease, Shanghai 200082, China
  • Received Date: 2018-03-19
  • Rev Recd Date: 2018-09-12

Abstract: Objective Systemic lupus erythematosus (SLE) models were mainly divided into spontaneous and induced models. Through the literature,spontaneous and induced SLE models and their main characteristics were reviewed, which provided references for the researchers to choose appropriate models for studying specific pathogenic mechanism and diagnostic criteria, searching for targeted treatment interventions and developing potential therapeutic drugs.

WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
Citation: WU Lan, CAI Tongkai, ZHANG Lichao, JIANG Yuanying, CAO Yongbing. Study on animal models and mechanisms of systemic lupus erythematosus[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 481-483,492. doi: 10.3969/j.issn.1006-0111.2018.06.001
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