Observation on the clinical curative effect of edaravone combined with ginkgo diterpene lactone on acute cerebral infarction

LI Di; SHAO Wei; TAI Zongguang; ZHAO Wenjun

doi:10.3969/j.issn.1006-0111.2018.01.017

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Objective To analyze the effect of edaravone combined with ginkgo diterpene lactone in treatment of acute cerebral infarction (ACI) and discuss the better clinical treatment to ACI. Methods 100 cases of ACI and who accepted treatments in our hospital were selected as the research objects in January 2014 to January 2015.50 patients as observation group were given the treatment of edaravone and ginkgo diterpene lactone at the same time,while other 50 patients as control group were merely given the treatment of ginkgo diterpene lactone.At the same time,both groups were given treatment of conventional therapy.The total neurological function,effective rate,adverse reactions,and the treatment satisfaction of both groups before and after the treatment were observed. Results There were no significant different of NIHSS score of two groups before treatment (P>0.05).After treatment,NIHSS score of the observation group was significantly lower than the control group (P<0.05).The total effective rate of observation group was 90%,which was significantly higher than the control group (66%,P<0.05).The main adverse reactions were rash,nausea,dizziness of two groups,and there were no significant different of adverse reactions rate of two groups through the treatment (P>0.05).The treatment of patients with satisfaction rate of observation group was 94%,which was significantly higher than control group (84%,P<0.05). Conclusion Edaravone combined with ginkgo diterpene lactone had a good effect on improving nerve function of ACI patients,which could improve the treatment of patients with satisfaction,high security,and could be recommended in clinical.

Observation on the clinical curative effect of edaravone combined with ginkgo diterpene lactone on acute cerebral infarction

1. No. 463 Hospital of PLA, Shenyang 110042, China

2. Institute for Drug and Instrument of Shenyang Military Region, Shenyang 110026, China

3. Changhai Hospital Affiliated to Second Military Medical University, Shanghai 200433, China;Hospital of No. 92330 Unit of PLA, Qingdao 266102, China

Received Date: 2017-07-29

Rev Recd Date: 2017-10-17

Key words:

Abstract: Objective To analyze the effect of edaravone combined with ginkgo diterpene lactone in treatment of acute cerebral infarction (ACI) and discuss the better clinical treatment to ACI. Methods 100 cases of ACI and who accepted treatments in our hospital were selected as the research objects in January 2014 to January 2015.50 patients as observation group were given the treatment of edaravone and ginkgo diterpene lactone at the same time,while other 50 patients as control group were merely given the treatment of ginkgo diterpene lactone.At the same time,both groups were given treatment of conventional therapy.The total neurological function,effective rate,adverse reactions,and the treatment satisfaction of both groups before and after the treatment were observed. Results There were no significant different of NIHSS score of two groups before treatment (P>0.05).After treatment,NIHSS score of the observation group was significantly lower than the control group (P<0.05).The total effective rate of observation group was 90%,which was significantly higher than the control group (66%,P<0.05).The main adverse reactions were rash,nausea,dizziness of two groups,and there were no significant different of adverse reactions rate of two groups through the treatment (P>0.05).The treatment of patients with satisfaction rate of observation group was 94%,which was significantly higher than control group (84%,P<0.05). Conclusion Edaravone combined with ginkgo diterpene lactone had a good effect on improving nerve function of ACI patients,which could improve the treatment of patients with satisfaction,high security,and could be recommended in clinical.

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Reference (13)

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Observation on the clinical curative effect of edaravone combined with ginkgo diterpene lactone on acute cerebral infarction

doi: 10.3969/j.issn.1006-0111.2018.01.017

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通讯作者: 陈斌, [email protected]

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