Neuronal and endocrine regulation of food intake

SUN Yang; WANG Pengyuan; LIU Xia

doi:10.3969/j.issn.1006-0111.2016.06.006

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The neuronal and hormonal regulations of food intake expand our knowledge about energy balance. The central nervous system integrates endocrine signals to regulate food intake and energy consumption. The nervous system and endocrine system interact with each other to regulate feeding behavior. This paper was a review of the neuronal and endocrine regulation of food intake, and offered a revealing insight for the study and treatment of metabolic disorders.

Neuronal and endocrine regulation of food intake

Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

Received Date: 2016-06-02

Rev Recd Date: 2016-07-19

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Abstract: The neuronal and hormonal regulations of food intake expand our knowledge about energy balance. The central nervous system integrates endocrine signals to regulate food intake and energy consumption. The nervous system and endocrine system interact with each other to regulate feeding behavior. This paper was a review of the neuronal and endocrine regulation of food intake, and offered a revealing insight for the study and treatment of metabolic disorders.

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[1]	Boguszewski CL, Paz-Filho G, Velloso LA. Neuroendocrine body weight regulation:integration between fat tissue, gastrointestinal tract, and the brain[J]. Endokrynol Pol, 2010, 61(2):194-206.
[2]	Morton GJ, Cummings DE, Baskin DG, et al. Central nervous system control of food intake and body weight[J]. Nature, 2006, 443(7109):289-295.
[3]	Kennedy GC. The role of depot fat in the hypothalamic control of food intake in the rat[J]. Proc R Soc Lond B Biol Sci, 1953, 140(901):578-596.
[4]	Schwartz MW, Woods SC, Porte D, Jr., et al. Central nervous system control of food intake[J]. Nature, 2000, 404(6778):661-671.
[5]	Gibbs J, Young RC, Smith GP. Cholecystokinin decreases food intake in rats[J]. J Comp Physiol Psychol, 1973, 84(3):488-495.
[6]	Cowley MA,Smart JL,Rubinstein M,et al.Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus[J].Nature,2001,411(6836):480-484.
[7]	Horvath TL. The hardship of obesity:a soft-wired hypothalamus[J]. Nat Neurosci, 2005, 8(5):561-565.
[8]	Myers MG, Jr., Munzberg H, Leinninger GM, et al. The geometry of leptin action in the brain:more complicated than a simple ARC[J]. Cell Metab, 2009, 9(2):117-123.
[9]	Grill HJ. Distributed neural control of energy balance:contributions from hindbrain and hypothalamus[J]. Obesity (Silver Spring), 2006, 14 Suppl 5:216S-221S.
[10]	Grill HJ. Leptin and the systems neuroscience of meal size control[J]. Front Neuroendocrinol, 2010, 31(1):61-78.
[11]	Ravinet Trillou C, Delgorge C, Menet C, et al. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity[J]. Int J Obes Relat Metab Disord, 2004, 28(4):640-648.
[12]	Farooqi S, O'Rahilly S. Genetics of obesity in humans[J]. Endocr Rev, 2006, 27(7):710-718.
[13]	Niswender KD, Morrison CD, Clegg DJ, et al. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus:a key mediator of insulin-induced anorexia[J]. Diabetes, 2003, 52(2):227-231.
[14]	Taniguchi CM, Emanuelli B, Kahn CR. Critical nodes in signalling pathways:insights into insulin action[J]. Nat Rev Mol Cell Biol, 2006, 7(2):85-96.
[15]	Ahima RS, Lazar MA. Adipokines and the peripheral and neural control of energy balance[J]. Mol Endocrinol, 2008, 22(5):1023-1031.
[16]	Moller DE. Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes[J]. Trends Endocrinol Metab, 2000, 11(6):212-217.
[17]	Wallenius K, Jansson JO, Wallenius V. The therapeutic potential of interleukin-6 in treating obesity[J]. Expert Opin Biol Ther, 2003, 3(7):1061-1070.
[18]	Cummings DE, Overduin J. Gastrointestinal regulation of food intake[J]. J Clin Invest, 2007, 117(1):13-23.
[19]	Drucker DJ. The biology of incretin hormones[J]. Cell Metab, 2006, 3(3):153-165.
[20]	Wynne K, Park AJ, Small CJ, et al. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects:a double-blind, randomized, controlled trial[J]. Diabetes, 2005, 54(8):2390-2395.
[21]	Degen L, Oesch S, Casanova M, et al. Effect of peptide YY3-36 on food intake in humans[J]. Gastroenterology, 2005, 129(5):1430-1436.
[22]	Kovacs EM, Lejeune MP, Westerterp-Plantenga MS. The effects of enterostatin intake on food intake and energy expenditure[J]. Br J Nutr, 2003, 90(1):207-214.
[23]	Fujimoto K, Fukagawa K, Sakata T, et al. Suppression of food intake by apolipoprotein A-IV is mediated through the central nervous system in rats[J]. J Clin Invest, 1993, 91(4):1830-1833.
[24]	Hollander P, Maggs DG, Ruggles JA, et al. Effect of pramlintide on weight in overweight and obese insulin-treated type 2 diabetes patients[J]. Obes Res, 2004, 12(4):661-668.
[25]	Obici S, Feng Z, Morgan K, et al. Central administration of oleic acid inhibits glucose production and food intake[J]. Diabetes, 2002, 51(2):271-275.

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Neuronal and endocrine regulation of food intake

doi: 10.3969/j.issn.1006-0111.2016.06.006

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通讯作者: 陈斌, [email protected]

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