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JIN Xilin, ZHANG Jie, JIANG Hailong, LU Yiming. The antitumor effect of snake venom toxins and its application in medical field[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 502-504,517. doi: 10.3969/j.issn.1006-0111.2015.06.006
Citation: JIN Xilin, ZHANG Jie, JIANG Hailong, LU Yiming. The antitumor effect of snake venom toxins and its application in medical field[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 502-504,517. doi: 10.3969/j.issn.1006-0111.2015.06.006

The antitumor effect of snake venom toxins and its application in medical field

doi: 10.3969/j.issn.1006-0111.2015.06.006
  • Received Date: 2013-09-01
  • Rev Recd Date: 2014-03-31
  • Objective To discuss the antitumor effect of snake venom toxins and its application in medical field. Methods To review the research progress of composition, the antitumor effect and mechanism of snake venom toxins. Results It was demonstrated that the snake venom toxins can stop various tumor cells from growing, and have the functions of killing the tumor cells, inducing cell death, and inhibition of angiogenesis. Conclusion It is an important direction in antitumor drug research and development to deeply research the composition and the mechanisms of action of the snake venom toxins.
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    [15] Chen X, Lv P, Liu J, et al. Apoptosis of human hepatocellular carcinoma cell (HepG2) induced by cardiotoxin III through sphase arrest [J].Toxicol Pathol, 2009,61(4): 307-315.
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    [18] Yeh CH,Peng HC,Yang RS,et al .Rhodostomin,a snake venom disintegrin,inhibits angiogenesis elicited by basic fibroblast growthfactor and suppresses tumor growth by a selective alpha(v)beta(3) blockade of endothelial cells[J].Mol Pharmacol,2001,59(5):1333-1342.
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The antitumor effect of snake venom toxins and its application in medical field

doi: 10.3969/j.issn.1006-0111.2015.06.006

Abstract: Objective To discuss the antitumor effect of snake venom toxins and its application in medical field. Methods To review the research progress of composition, the antitumor effect and mechanism of snake venom toxins. Results It was demonstrated that the snake venom toxins can stop various tumor cells from growing, and have the functions of killing the tumor cells, inducing cell death, and inhibition of angiogenesis. Conclusion It is an important direction in antitumor drug research and development to deeply research the composition and the mechanisms of action of the snake venom toxins.

JIN Xilin, ZHANG Jie, JIANG Hailong, LU Yiming. The antitumor effect of snake venom toxins and its application in medical field[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 502-504,517. doi: 10.3969/j.issn.1006-0111.2015.06.006
Citation: JIN Xilin, ZHANG Jie, JIANG Hailong, LU Yiming. The antitumor effect of snake venom toxins and its application in medical field[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 502-504,517. doi: 10.3969/j.issn.1006-0111.2015.06.006
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