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Volume 33 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2015  >  33(4): 380-382,384

LIN Xiuli, SHI Hekun, CHEN Shangyu, CHEN Jinshan. Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 380-382,384. doi: 10.3969/j.issn.1006-0111.2015.04.024
Citation: LIN Xiuli, SHI Hekun, CHEN Shangyu, CHEN Jinshan. Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 380-382,384. doi: 10.3969/j.issn.1006-0111.2015.04.024
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Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema

doi: 10.3969/j.issn.1006-0111.2015.04.024

  • Department of Pharmacy, No. 175 Hospital of PLA, Zhangzhou 363000, China

  • Received Date: 2014-01-14
  • Rev Recd Date: 2014-07-02
  • Objective To assess the effects of compound glycyrrhizin tablets for chronic eczema patients using the Meta-analysis method. Methods The national literatures related to random control clinical trials on compound glycyrrhizin tablets for treating chronic eczema were retrieved. The method recommend by the cochrane collaboration to perform a Meta-analysis of randomized controlled trail(RCT)in RevMan 5.0 was applied. Results Nine articles were included, eight hundred and thirty patients were enrolled, and there were four hundred and fifteen cases for both the treatment group and control group. The results showed that both curative effect and safety of the treatment group with compound glycyrrhizin were better than that of the control group. Conclusion Compound glycyrrhizin had certain curative effect in the treatment of chronic eczema. It was safe and with less adverse effect. However, it still needs more strict and multicentre randomized double-blind control trial to provide more effective and convinced evidence.
  • [1] 张 伟,郭艳梅,邓 旭.复方甘草酸苷治疗慢性湿疹的疗效观察[J].中国现代医生,2010,48(8):128-129.
    [2] 张学军.皮肤性病学[M].6版.北京:人民卫生出版社,2007:100-102.
    [3] Jadad AR,Moore RA,Carroll D,et al. Assessing the quality of reports of randomized clinical trials∶is blinding necessary[J].Control Clin Trials,1996,17(1):1-12.
    [4] 吴学敬.复方甘草酸苷治疗慢性湿疹28例疗效观察[J].中国现代药物应用,2009,3(13):120-121.
    [5] 叶 萍,黄伟林,郑 力,等.复方甘草酸苷辅助左西替利嗪治疗慢性湿疹43例[J].中国药业,2010,19(5):54-55.
    [6] 吴 波,余振东,刘 颜.依匹斯汀联合复方甘草酸苷治疗慢性湿疹临床观察[J].中国医院用药评价与分析,2009,9(5):383-384.
    [7] 张 伟,郭艳梅,邓 旭.复方甘草酸苷治疗慢性湿疹的疗效观察[J].中国现代医生,2010,48(8):128-129.
    [8] 张文宪,原凡惠,.复方甘草酸苷治疗慢性湿疹34例临床观察[J].中国现代药物应用,2010,4(5):98.
    [9] 赵 欢,黄丽苹.复方甘草酸苷片联合西替利嗪片治疗慢性湿疹75 例疗效观察[J].中国药物经济学,2012(2):161-162.
    [10] 王秋佳.复方甘草酸苷联合依匹斯汀胶囊治疗慢性湿疹的疗效观察[J].中国药物经济学,2011,9(29):342-343.
    [11] 苏伟才.复方甘草酸苷片联合复方氟米松软膏治疗慢性湿疹的临床分析[J].中国现代医生,2011,49(7):342-343.
    [12] 李 杰.联合用药治疗慢性湿疹的疗效分析[J].求医问药,2012,10(5):269.
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Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema

doi: 10.3969/j.issn.1006-0111.2015.04.024
  • Department of Pharmacy, No. 175 Hospital of PLA, Zhangzhou 363000, China
  • Received Date: 2014-01-14
  • Rev Recd Date: 2014-07-02

Abstract: Objective To assess the effects of compound glycyrrhizin tablets for chronic eczema patients using the Meta-analysis method. Methods The national literatures related to random control clinical trials on compound glycyrrhizin tablets for treating chronic eczema were retrieved. The method recommend by the cochrane collaboration to perform a Meta-analysis of randomized controlled trail(RCT)in RevMan 5.0 was applied. Results Nine articles were included, eight hundred and thirty patients were enrolled, and there were four hundred and fifteen cases for both the treatment group and control group. The results showed that both curative effect and safety of the treatment group with compound glycyrrhizin were better than that of the control group. Conclusion Compound glycyrrhizin had certain curative effect in the treatment of chronic eczema. It was safe and with less adverse effect. However, it still needs more strict and multicentre randomized double-blind control trial to provide more effective and convinced evidence.

LIN Xiuli, SHI Hekun, CHEN Shangyu, CHEN Jinshan. Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 380-382,384. doi: 10.3969/j.issn.1006-0111.2015.04.024
Citation: LIN Xiuli, SHI Hekun, CHEN Shangyu, CHEN Jinshan. Meta-analysis of compound glycyrrhizin tablets in treatment of chronic eczema[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(4): 380-382,384. doi: 10.3969/j.issn.1006-0111.2015.04.024
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