Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 33 Issue 2
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2015  >  33(2): 147-149,170

PAN Hongtao, YANG Zongxing, ZHAO Wencui, WANG Yanping, SONG Haiyan, ZHANG Qi. Study on anti-microbial activity of allicin on campylobacter jejuni[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 147-149,170. doi: 10.3969/j.issn.1006-0111.2015.02.014
Citation: PAN Hongtao, YANG Zongxing, ZHAO Wencui, WANG Yanping, SONG Haiyan, ZHANG Qi. Study on anti-microbial activity of allicin on campylobacter jejuni[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 147-149,170. doi: 10.3969/j.issn.1006-0111.2015.02.014
shu

Study on anti-microbial activity of allicin on campylobacter jejuni

doi: 10.3969/j.issn.1006-0111.2015.02.014
  • 1.

    Department of Pharmacy, No.208 Hospital of PLA, Changchun 130062, China

  • 2.

    Department of Pharmacy, No.208 Hospital of PLA, Changchun 130062, China;College of Pharmacy, Yanbian University, Yanji 133000, China

  • Received Date: 2014-03-03
  • Rev Recd Date: 2014-09-24
  • Objective To study the anti-microbial activity and strength of allicin on Campylobacter jejuni. Methods Disc diffusion method (K-B) was used to determine the diameter of the bacteriostatic ring. The minimal inhibitory concentration (MIC) of allicin, ciprofloxacin and erythromycin were detected by constant broth dilution method, respectively.The minimal inhibitory concentrations and bacteriostatic rate of allicin,ciprofloxacin and erythromycin were compared. Results The anti-microbial activity on Campylobacter jejuni of allicin (MIC 12.8 μg/ml, bactetiostatic rate 90.40%) was better than that of ciprofloxacin (MIC 20.48 μg/ml, bactetiostatic rate 90.21%) and erythromycin (MIC 35.84 μg/ml, bactetiostatic rate 90.33%). Conclusion Allicin has anti-microbial activity on Campylobacter jejuni in vitro.
  • [1] Cavallito CJ,Bailey JH.Allicin,the antibacterial principle of Allium sativum. I. isolation,physicalproperties,and antibacterial action[J]. Am Chem Soc,1944,66(11):1950.
    [2] Lu X, Samuelson DR, Rasco BA, et al.Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms[J]. J Antimicrob Chemother,2012,67(8):1915-1926.
    [3] 骆海明,陈 倩.弯曲菌菌种冷冻保存及复苏方法研究[J]. 中国食品卫生杂志,2007,19(6):518.
    [4] 韩新锋,刘书亮,张晓利,等.鸡肉空肠弯曲杆菌的分离鉴定及耐药性分析[J]. 中国人兽共患病学报,2012,28(1):31.
    [5] Clinical and Laboratory Stanndards Institute.Approved standard M07-A8 methods for dilution antimicrobial susceptibiolity tests for bacteria that grow aerobically[S]. 8th ed.Villanova, PA:NCCLS,2009,29(2).
    [6] 孙长贵,曾向铭,杨 燕.肉汤稀释法酵母菌药物敏感性试验及质量控制介绍[J]. 江西医学检验,2007,25(1):57.
    [7] 陈振华,刘文恩. 碳青霉烯酶研究进展[J]. 国际检验医学杂志,2010,31(6):848.
    [8] 国家药典委员会.中华人民共和国药典2010年版一部[S]. 北京:中国医药科技出版社,2010:23.
  • 加载中
通讯作者: 陈斌, [email protected]
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2596) PDF downloads(112) Cited by()

Related
Proportional views

Study on anti-microbial activity of allicin on campylobacter jejuni

doi: 10.3969/j.issn.1006-0111.2015.02.014
  • 1. Department of Pharmacy, No.208 Hospital of PLA, Changchun 130062, China
  • 2. Department of Pharmacy, No.208 Hospital of PLA, Changchun 130062, China;College of Pharmacy, Yanbian University, Yanji 133000, China
  • Received Date: 2014-03-03
  • Rev Recd Date: 2014-09-24

Abstract: Objective To study the anti-microbial activity and strength of allicin on Campylobacter jejuni. Methods Disc diffusion method (K-B) was used to determine the diameter of the bacteriostatic ring. The minimal inhibitory concentration (MIC) of allicin, ciprofloxacin and erythromycin were detected by constant broth dilution method, respectively.The minimal inhibitory concentrations and bacteriostatic rate of allicin,ciprofloxacin and erythromycin were compared. Results The anti-microbial activity on Campylobacter jejuni of allicin (MIC 12.8 μg/ml, bactetiostatic rate 90.40%) was better than that of ciprofloxacin (MIC 20.48 μg/ml, bactetiostatic rate 90.21%) and erythromycin (MIC 35.84 μg/ml, bactetiostatic rate 90.33%). Conclusion Allicin has anti-microbial activity on Campylobacter jejuni in vitro.

PAN Hongtao, YANG Zongxing, ZHAO Wencui, WANG Yanping, SONG Haiyan, ZHANG Qi. Study on anti-microbial activity of allicin on campylobacter jejuni[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 147-149,170. doi: 10.3969/j.issn.1006-0111.2015.02.014
Citation: PAN Hongtao, YANG Zongxing, ZHAO Wencui, WANG Yanping, SONG Haiyan, ZHANG Qi. Study on anti-microbial activity of allicin on campylobacter jejuni[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 147-149,170. doi: 10.3969/j.issn.1006-0111.2015.02.014
shu

    HTML

Reference (8)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: [email protected]

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return