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Volume 33 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2015  >  33(2): 110-113

LIU Xuemei, LIU Zhihong, ZHANG Jing, CHI Jie, YANG Lina, SONG Hongtao. Study progress on clinical application and side effects of Tripterygium wilfordii[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 110-113. doi: 10.3969/j.issn.1006-0111.2015.02.004
Citation: LIU Xuemei, LIU Zhihong, ZHANG Jing, CHI Jie, YANG Lina, SONG Hongtao. Study progress on clinical application and side effects of Tripterygium wilfordii[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 110-113. doi: 10.3969/j.issn.1006-0111.2015.02.004
shu

Study progress on clinical application and side effects of Tripterygium wilfordii

doi: 10.3969/j.issn.1006-0111.2015.02.004
  • 1.

    Department of Pharmacy, Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, China;School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China

  • 2.

    Department of Pharmacy, Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, China

  • Received Date: 2013-11-25
  • Rev Recd Date: 2014-09-09
  • Tripterygium wilfordii has been widely used in clinic for the treatment of autoimmune diseases, such as nephrotic syndrome, rheumatoid arthritis, systemic lupus erythematosus, and the curative effect is significant. But it has toxic and side effects for liver, kidney, reproductive system, etc. The side effects of Tripterygium wilfordii are the main obstacles for the usage and promotion. The literature reports about the clinical application and side effect of Tripterygium wilfordii are reviewed in this paper, which provides reference for usage in clinic.
  • [1] 雷载权.中药学[M].上海:上海科学技术出版社,1995:112-113.
    [2] 徐央丽. 雷公藤研究进展[J].现代中西医结合杂志,2008,17(12):1941-1942.
    [3] 于永敏. 雷公藤片联合帕夫林治疗类风湿性关节炎活动期的观察[J].河南职工医学院学报,2013,25(1):16-18.
    [4] Ge YC,Xie HL,Li SJ,et al. Treatment of diabetic nephropathy with Tripterygium wilfordii Hook F. extract: a prospective, randomized, controlled clinical trial[J].J Transl Med,2013,11(1):134-142.
    [5] 常雪静,夏宇欧. 不同方法治疗肾病综合征临床疗效分析[J].中外医疗,2013,(12):58-60.
    [6] 刘玉平. 小剂量糖皮质激素与雷公藤多苷联合治疗IgA 肾病蛋白尿患者的疗效观察[J].临床和实验医学杂志,2013,12(13):1019-1021.
    [7] Canter PH,Lee HS,Ernst E. A systematic review of randomised clinical trials of Tripterygium wilfordii for rheumatoid arthritis[J].Phytomedicine,2006,13(5):371-377.
    [8] Ji SM,Wang QW,Chen JS,et al. Clinical trial of Tripterygium wilfordii Hook F. in human kidney transplantation in China[J].Transplant Proc,2006,38(5):1274-1279.
    [9] 杨 竹. 雷公藤片治疗类风湿性关节炎74例[J].临床和实验医学杂志,2013,12(9):659-661.
    [10] 冯 林,马 玲. 治疗类风湿性关节炎疗效及安全性观察[J].传统医药,2011,20(14):76-77.
    [11] 张小蒙. 雷公藤的药理作用和临床应用研究进展[J].临床合理用药杂志,2012,5(7):180.
    [12] 唐 宁,周红霞,周东蕊.中国雷公藤制剂治疗系统性红斑狼疮疗效的Meta分析[J].南京晓庄学院学报,2012,(3):68-71.
    [13] 张秋萍,宋洪涛. 雷公藤制剂研究进展[J].中国药师,2009,12(7):881-883.
    [14] 张金梅. 雷公藤几种疗效的临床分析[J].临床药学,2012,31(14):34.
    [15] 柴 智,周文静,高 丽,等. 雷公藤肝毒性及其作用机制的研究进展[J].中国实验方剂学杂志,2011,17(7):243-246.
    [16] 薛 璟, 贾晓斌, 谭晓斌, 等. 雷公藤化学成分及其毒性研究[J].中华中医药杂志,2010,,25(5):730-731.
    [17] 孙 新, 张素敏, 田春华, 等. 雷公藤及其安全性[J].中国新药杂志,2001,10(7):39-543.
    [18] 王玉玲,张立明,辛荣贞,等.雷公藤多苷治疗儿童过敏性紫癜性肾炎56例临床观察[J].中国煤炭工业杂志,2007,2(10):1611.
    [19] 姚骥如,孙 莹,罗顺葵,等. 雷公藤多苷的临床应用进展[J].中国新药与临床杂志,2010,38(3):26-29.
    [20] 印成霞. 55例雷公藤多甙片/雷公藤多苷片致不良反应文献分析[J].中国药物警戒,2013,10(8):478-482.
    [21] 张敬之. 雷公藤多苷联合红霉素治疗急性滴型银屑病临床观察[J].浙江中西医结合杂志,2013,23(5):373-374.
    [22] 莫惠平,潘秋荣,谭柳群. 雷公藤多苷的不良反应及防治措施[J].中国中西医杂志,2003,23(5):386-387.
    [23] 高 丽,白 赟,柴 智,等. 雷公藤毒性反应研究进展[J].中国中医药信息杂志,2012,19(4):107-110.
    [24] 柯坤字. 雷公藤多苷片引起肝损害一例报告[J].实用临床医学杂志社,2009,10(7):40-42.
    [25] 梁伟坤,邝俊建. 雷公藤及其制剂相关肝损害国内文献分析[J].中国药物应用与检测,2010,8(3):169-172.
    [26] 倪 军,魏 升,俞东容,等. 雷公藤中毒合并横纹肌溶解致急性肾衰竭1例[J].中国中西医结合肾病杂志,2010,11(2):163.
    [27] 潘艳琳,林丽芳,于 静. 雷公藤不良反应75例分析[J].海峡药学,2011,23(8):163.
    [28] 陈利欣,李 晶. 雷公藤的肾毒性作用及其防治[J].山东医药,2009,49(37):113-114.
    [29] Chen X,Chen SL. A woman with premature ovarian failure induced by Tripterygium Wilfordii Hook f. gives birth to a healthy child[J].Fertil Steril,2001,96(1):e19-21.
    [30] 唐 永,张 霞,苏蓓蓓. 雷公藤在皮肤科应用中的不良反应(附163例临床分析)[J].临床皮肤科杂志,1998,27(6):377.
    [31] 李 平,陈 钢,赵怡蕊,等. 雷公藤的不良反应[J].药物不良反应杂志,2002,(4):238-241.
    [32] 徐 志,虞飞燕,范贤斌. 雷公藤多苷致再生障碍性贫血2例报道[J].浙江中西医结合杂志,2005,15(11):704-705.
    [33] 孙鲁英,王耀献. 雷公藤多苷致重度贫血一例[J].临床内科杂志,2004,22(2):85.
    [34] 邹爱英,刘秀书. 雷公藤多苷片的不良反应及防治对策[J].天津药学,2008, 20(1):25-26.
    [35] 靳丽萍,韩宝利. 雷公藤致心动过缓7例的临床辨析[J].心血管康复医学杂志,2001,10(3):267-268.
    [36] 运乃茹,甘井山. 雷公藤及其制剂临床不良反应概述[J].天津药学,2012,24(1):18-19.
    [37] 潘贵光,高文平. 雷公藤多苷片致过敏反应1例[J].药物不良反应与相互作用,2003,21(1):52.
    [38] 刘光灿. 雷公藤片致面部色素沉着1例[J].菏泽医专学报,2004,16(1):19.
    [39] 冯 群,栾永福,孙 蓉. 基于功效和物质基础的雷公藤毒性研究进展[J].中国药物警戒,2013,10(2):88-91.
    [40] 覃俏峰. 雷公藤的不良反应及中药配伍减毒分析[J].中医中药,2011,18(10):96-97.
    [41] 刘为萍,刘素香,唐慧珠,等. 雷公藤研究新进展[J].中草药,2010,40(7):192-195.
    [42] 邓书鸿,聂 磊. 中药谱效关系的分析方法及数据处理技术研究进展[J].中药材,2010,33(11):1819-1823.
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Study progress on clinical application and side effects of Tripterygium wilfordii

doi: 10.3969/j.issn.1006-0111.2015.02.004
  • 1. Department of Pharmacy, Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, China;School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China
  • 2. Department of Pharmacy, Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, China
  • Received Date: 2013-11-25
  • Rev Recd Date: 2014-09-09

Abstract: Tripterygium wilfordii has been widely used in clinic for the treatment of autoimmune diseases, such as nephrotic syndrome, rheumatoid arthritis, systemic lupus erythematosus, and the curative effect is significant. But it has toxic and side effects for liver, kidney, reproductive system, etc. The side effects of Tripterygium wilfordii are the main obstacles for the usage and promotion. The literature reports about the clinical application and side effect of Tripterygium wilfordii are reviewed in this paper, which provides reference for usage in clinic.

LIU Xuemei, LIU Zhihong, ZHANG Jing, CHI Jie, YANG Lina, SONG Hongtao. Study progress on clinical application and side effects of Tripterygium wilfordii[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 110-113. doi: 10.3969/j.issn.1006-0111.2015.02.004
Citation: LIU Xuemei, LIU Zhihong, ZHANG Jing, CHI Jie, YANG Lina, SONG Hongtao. Study progress on clinical application and side effects of Tripterygium wilfordii[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 110-113. doi: 10.3969/j.issn.1006-0111.2015.02.004
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