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Volume 33 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2015  >  33(2): 106-109,170

LI Wenqing, ZOU Hao, ZHONG Yanqiang. Analysis of problems on tumor-targeting drug delivery system[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 106-109,170. doi: 10.3969/j.issn.1006-0111.2015.02.003
Citation: LI Wenqing, ZOU Hao, ZHONG Yanqiang. Analysis of problems on tumor-targeting drug delivery system[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 106-109,170. doi: 10.3969/j.issn.1006-0111.2015.02.003
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Analysis of problems on tumor-targeting drug delivery system

doi: 10.3969/j.issn.1006-0111.2015.02.003

  • Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2014-01-14
  • Rev Recd Date: 2014-09-23
  • Objective To analyze the current problems on tumor-targeting nanoparticle drug delivery system. Methods Recent researches of tumor-targeting nanoparticle drug delivery system were collected, read and summarized. Results Three research fields on tumor-targeting nanoparticle drug delivery system were reviewed in this article. Conclusion Not only a deeper understanding of the human physiology and tumor biology, but changes in strategies and experimental methods are needed to make new achievements on nanoparticle drug delivery system.
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    [2] 高 芸,李少一,商雪莹,等. FAT10过表达对肝癌细胞HepG2侵袭及迁移能力的影响[J].实用预防医学, 2013,20(5):517-520.
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    [9] Rooy I, Mastrobattista E, Storm G, et al. Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain[J]. J Control Release, 2011,150(1): 30-36.
    [10] Bareford LM, Swann PW. Endocytic mechanisms for targeted drug delivery[J]. Adv Drug Deliv Rev, 2007,59(8) :748-758.
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    [13] Chen H, Kim S, He W, et al. Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo Forster resonance energy transfer imaging[J]. Langmuir, 2008,24(10): 5213-5217.
    [14] Chen H, Kim S, Li L, et al. Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging[J]. Proc Natl Acad Sci USA, 2008,105(18): 6596-6601.
    [15] Koo AN, Min KH, Lee HJ, et al.Tumor accumulation and antitumor efficacy of docetaxel-loaded core-shell-corona micelles with shell-specific redox-responsive cross-links[J]. Biomaterials, 2012,33(5): 1489-1499.
    [16] Ishida T, Ichihara M, Wang X, et al. Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes[J]. J Control Release, 2006,115(3): 243-250.
    [17] Lu W,Wan J,She Z,et al.Brain delivery property and accelerated blood clearance of cationic albumin conjugated pegylated nanoparticle[J].J Control Release,2007,118(1):38-53.
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Analysis of problems on tumor-targeting drug delivery system

doi: 10.3969/j.issn.1006-0111.2015.02.003
  • Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2014-01-14
  • Rev Recd Date: 2014-09-23

Abstract: Objective To analyze the current problems on tumor-targeting nanoparticle drug delivery system. Methods Recent researches of tumor-targeting nanoparticle drug delivery system were collected, read and summarized. Results Three research fields on tumor-targeting nanoparticle drug delivery system were reviewed in this article. Conclusion Not only a deeper understanding of the human physiology and tumor biology, but changes in strategies and experimental methods are needed to make new achievements on nanoparticle drug delivery system.

LI Wenqing, ZOU Hao, ZHONG Yanqiang. Analysis of problems on tumor-targeting drug delivery system[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 106-109,170. doi: 10.3969/j.issn.1006-0111.2015.02.003
Citation: LI Wenqing, ZOU Hao, ZHONG Yanqiang. Analysis of problems on tumor-targeting drug delivery system[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(2): 106-109,170. doi: 10.3969/j.issn.1006-0111.2015.02.003
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