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Volume 33 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2015  >  33(1): 72-72,87

ZHOU Fuhua. Clinical observation on local reaction of the subcutaneous etanercept for treating ankylosing spondylitis with different injection site[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 72-72,87. doi: 10.3969/j.issn.1006-0111.2015.01.020
Citation: ZHOU Fuhua. Clinical observation on local reaction of the subcutaneous etanercept for treating ankylosing spondylitis with different injection site[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 72-72,87. doi: 10.3969/j.issn.1006-0111.2015.01.020
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Clinical observation on local reaction of the subcutaneous etanercept for treating ankylosing spondylitis with different injection site

doi: 10.3969/j.issn.1006-0111.2015.01.020

  • Department of Endocrinology, Xiaogan Central Hospital, Xiaogan 432000, China

  • Received Date: 2013-09-25
  • Rev Recd Date: 2014-06-18
  • Objective To observe adverse reactions of the subcutaneous etanercept with different injection site. Methods 60 patients with ankylosing spondylitis treated in our hospital from March 2012 to March 2013 were divided randomly into two groups.A group were injected deltoid subcutaneous,and B group were injected abdominal subcutaneous.The local adverse skin reactions were compared between the two groups. Results 10 cases occurred adverse reactions from A group,and only 1case occurred adverse reactions from group B.The incidence of adverse reactions of injected subcutaneously significantly lower than deltoid subcutaneous (P<0.05). Conclusion Abdominal subcutaneous etanercept could reduces the incidence of adverse reactions,which was worthy of clinical application.
  • [1] 汪年松,冯承德.风湿病学[M].上海:上海交通大学出版社,2009:234-237.
    [2] Breedveld FC.Tumour necrosis factor antagonists:infliximab,adalimumab and etanercept[J].Ned Tijdschr Geneeskd,2005,149(41):2273-2277.
    [3] Clelland S,Hunek JR.Etanercept injection site reaction[J].Dermatol Nurs,2005,17(5):375.
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通讯作者: 陈斌, [email protected]
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Clinical observation on local reaction of the subcutaneous etanercept for treating ankylosing spondylitis with different injection site

doi: 10.3969/j.issn.1006-0111.2015.01.020
  • Department of Endocrinology, Xiaogan Central Hospital, Xiaogan 432000, China
  • Received Date: 2013-09-25
  • Rev Recd Date: 2014-06-18

Abstract: Objective To observe adverse reactions of the subcutaneous etanercept with different injection site. Methods 60 patients with ankylosing spondylitis treated in our hospital from March 2012 to March 2013 were divided randomly into two groups.A group were injected deltoid subcutaneous,and B group were injected abdominal subcutaneous.The local adverse skin reactions were compared between the two groups. Results 10 cases occurred adverse reactions from A group,and only 1case occurred adverse reactions from group B.The incidence of adverse reactions of injected subcutaneously significantly lower than deltoid subcutaneous (P<0.05). Conclusion Abdominal subcutaneous etanercept could reduces the incidence of adverse reactions,which was worthy of clinical application.

ZHOU Fuhua. Clinical observation on local reaction of the subcutaneous etanercept for treating ankylosing spondylitis with different injection site[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 72-72,87. doi: 10.3969/j.issn.1006-0111.2015.01.020
Citation: ZHOU Fuhua. Clinical observation on local reaction of the subcutaneous etanercept for treating ankylosing spondylitis with different injection site[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(1): 72-72,87. doi: 10.3969/j.issn.1006-0111.2015.01.020
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