Analyzation and suggestion of irregular usage of drug prescriptions in clinic

LIU Xia

doi:10.3969/j.issn.1006-0111.2014.06.017

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Objective To offer suggestions for how to administrate irregular usage of drug prescriptions in clinic. Methods The objective reasons and the hidden danger of irregular usage of drug prescriptions were analyzed. The existing international administration experience was searched and descriptive analysis was conducted. Results The existence of off-label use was rational because the drug instruction had its loophole, and the information usually was lagged updated. However, off-label use could increase risks for both patients and doctors, which should be administrated by the government. International experience includes: set up clinical evidence references, encourage drug companies to update instructions in time;establish independent drug information organization. Conclusion Irregular usage of drug prescriptions had its rationality and necessity. Relative regulations should be formulated in China as soon as possible. Irregular usage of drug prescriptions should follow certain principles. Active information support should be offered from related organization. Media administration and public education should be focused.

Analyzation and suggestion of irregular usage of drug prescriptions in clinic

Department of Pharmacy, Shanghai 6th People's Hospital, Shanghai 200233, China

Received Date: 2013-08-11

Rev Recd Date: 2013-11-25

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Abstract: Objective To offer suggestions for how to administrate irregular usage of drug prescriptions in clinic. Methods The objective reasons and the hidden danger of irregular usage of drug prescriptions were analyzed. The existing international administration experience was searched and descriptive analysis was conducted. Results The existence of off-label use was rational because the drug instruction had its loophole, and the information usually was lagged updated. However, off-label use could increase risks for both patients and doctors, which should be administrated by the government. International experience includes: set up clinical evidence references, encourage drug companies to update instructions in time;establish independent drug information organization. Conclusion Irregular usage of drug prescriptions had its rationality and necessity. Relative regulations should be formulated in China as soon as possible. Irregular usage of drug prescriptions should follow certain principles. Active information support should be offered from related organization. Media administration and public education should be focused.

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Reference (13)

[1]	American Society of Hospita1 Pharmacists.ASHP statement on the use of medications for unlabeled uses[J].Am J Hosp Pharm,1992,49(8):2006.
[2]	Stafford RS.Regulating off-label drug use-rethinking the role of the FDA[J].N Engl J Med,2008,358(14):1427.
[3]	张伶俐, 李幼平, 黄亮等.四川大学华西第二医院2010年儿科门诊患儿超说明书用药情况调查[J].中国循证医学杂志2012, 12(3): 267-273.
[4]	陈冬裕.对现行中成药说明书的调查和思考[J].中国药房,2009, 20(9): 718-720.
[5]	苏洽玉,陈海坤.558份化学药品说明书的调查分析[J].中国药房,2008,04(35): 316-318.
[6]	杨玉龙.正确认识超说明书用药[J].首都医药,2012,10: 42-43.
[7]	宋儒亮.超说明书用药患者与医生的权益保护[J].中国处方药,2012, 12(106): 10-11.
[8]	广东省药学会.药品未注册用法专家共识[Z].粤药会[2010] 8号,2010.
[9]	张伶俐, 李幼平, 曾力楠,等.15国超说明书用药政策的循证评价[J].中国循证医学杂志,2012,12(4):426-435.
[10]	Cheng AC, Robinson PM, Harvey K.Off-label use of medicines:consensus recommendations for evaluating appropriateness[J].MIA, 2007, 186(7): 379-380.
[11]	Australian Government Department of Health and Ageing. Health and ageing thesaurus[EB/OL]. (2011-11-26)[2013-06-28]http://www.health.gov.au/internet/main/publishing.nsf/Content/health-thesaurus.htm.
[12]	AHFS. About AHFS[EB/OL]. (2013-03-26)[2013-06-20]http://www.ahfsdruginformation.com/about_ahfs/.
[13]	刘宇.药品说明书之外用法的法律风险提示及对策[J].协和医学杂志,2010,1(1):1.

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Analyzation and suggestion of irregular usage of drug prescriptions in clinic

doi: 10.3969/j.issn.1006-0111.2014.06.017

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通讯作者: 陈斌, [email protected]

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