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ZHAO Rang, LIU Xin. Efficacy observation of defibrase combined standard regimen in treatment of non ST segment elevation myocardial infarction[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 118-120. doi: 10.3969/j.issn.1006-0111.2014.02.011
Citation: ZHAO Rang, LIU Xin. Efficacy observation of defibrase combined standard regimen in treatment of non ST segment elevation myocardial infarction[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 118-120. doi: 10.3969/j.issn.1006-0111.2014.02.011

Efficacy observation of defibrase combined standard regimen in treatment of non ST segment elevation myocardial infarction

doi: 10.3969/j.issn.1006-0111.2014.02.011
  • Received Date: 2013-05-11
  • Rev Recd Date: 2013-11-03
  • Objective To discuss the effectiveness of defibrase in the treatment of NSTEMI and effects of defibrase on the prognosis of NSTEMI. Methods 86 patients with NSTEMI were randomly divided into treatment group and control group, patients received standard treatment, and treatment group added defibrase. Results The effective rates of the treatment group was significantly higher than control group, the level of myocardial enzymes and hs-CRP was significantly lower than control group(P<0.05). Conclusion Based on standard treatment with defibrase was more conducive to improve clinical symptoms, reduce complications, and there were some inhibitory effect on the development of myocardial remodeling after myocardial infarction.
  • [1] 史继学,孔繁亭.急诊医学[M].3版.北京:中国医药科技出版社,2008:145.
    [2] 张象豫.药物临床信息[M].重庆:重庆出版社,2008:856.
    [3] Rajendran K, Devarajan N, Ganesan M, et al. Obesity, inflammation and acute myocardial infarction-expression of leptin, IL-6 and high sensitivity-CRP in chennai based population[J].Thromb J,2012,10(1):13.
    [4] Ghattas MH, Abo-Elmatty DM, El-Eraki AZ. C-reactive protein 1059G/C gene polymorphism, C-reactive protein levels and acute myocardial infarction[J].J Cardiovasc Med (Hagerstown), 2012,13(11):716-719.
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通讯作者: 陈斌, [email protected]
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Efficacy observation of defibrase combined standard regimen in treatment of non ST segment elevation myocardial infarction

doi: 10.3969/j.issn.1006-0111.2014.02.011

Abstract: Objective To discuss the effectiveness of defibrase in the treatment of NSTEMI and effects of defibrase on the prognosis of NSTEMI. Methods 86 patients with NSTEMI were randomly divided into treatment group and control group, patients received standard treatment, and treatment group added defibrase. Results The effective rates of the treatment group was significantly higher than control group, the level of myocardial enzymes and hs-CRP was significantly lower than control group(P<0.05). Conclusion Based on standard treatment with defibrase was more conducive to improve clinical symptoms, reduce complications, and there were some inhibitory effect on the development of myocardial remodeling after myocardial infarction.

ZHAO Rang, LIU Xin. Efficacy observation of defibrase combined standard regimen in treatment of non ST segment elevation myocardial infarction[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 118-120. doi: 10.3969/j.issn.1006-0111.2014.02.011
Citation: ZHAO Rang, LIU Xin. Efficacy observation of defibrase combined standard regimen in treatment of non ST segment elevation myocardial infarction[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(2): 118-120. doi: 10.3969/j.issn.1006-0111.2014.02.011
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