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WANG Tao. Decreasing tablet strength of magnesium stearate in direct compression technology[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(1): 19-22. doi: 10.3969/j.issn.1006-0111.2014.01.005
Citation: WANG Tao. Decreasing tablet strength of magnesium stearate in direct compression technology[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(1): 19-22. doi: 10.3969/j.issn.1006-0111.2014.01.005

Decreasing tablet strength of magnesium stearate in direct compression technology

doi: 10.3969/j.issn.1006-0111.2014.01.005
  • Received Date: 2013-06-28
  • Rev Recd Date: 2013-11-06
  • Magnesium stearate as a lubricant plays an important role in the direct compression of tablet technology, but the use of magnesium stearate often causes negative effect on tablet strength. The reasons of decreasing tablet strength from the aspects of excipients classification, particle size, blending time and lubricant concentration were briefly analyzed, which was helpful for the promotion and improvement of the tablet manufacturing level.
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Decreasing tablet strength of magnesium stearate in direct compression technology

doi: 10.3969/j.issn.1006-0111.2014.01.005

Abstract: Magnesium stearate as a lubricant plays an important role in the direct compression of tablet technology, but the use of magnesium stearate often causes negative effect on tablet strength. The reasons of decreasing tablet strength from the aspects of excipients classification, particle size, blending time and lubricant concentration were briefly analyzed, which was helpful for the promotion and improvement of the tablet manufacturing level.

WANG Tao. Decreasing tablet strength of magnesium stearate in direct compression technology[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(1): 19-22. doi: 10.3969/j.issn.1006-0111.2014.01.005
Citation: WANG Tao. Decreasing tablet strength of magnesium stearate in direct compression technology[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(1): 19-22. doi: 10.3969/j.issn.1006-0111.2014.01.005
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