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Volume 31 Issue 3
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2013  >  31(3): 207-209

QIAN Xiao-ying. Blood gas index analysis and clinical effect comparison of ulinastatin combined with NIPPV in treatment of 18 ALI patients[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 207-209. doi: 10.3969/j.issn.1006-0111.2013.03.013
Citation: QIAN Xiao-ying. Blood gas index analysis and clinical effect comparison of ulinastatin combined with NIPPV in treatment of 18 ALI patients[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 207-209. doi: 10.3969/j.issn.1006-0111.2013.03.013
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Blood gas index analysis and clinical effect comparison of ulinastatin combined with NIPPV in treatment of 18 ALI patients

doi: 10.3969/j.issn.1006-0111.2013.03.013

  • Department of Respiratory, the people's Hospital of Wenzhou, Zhejiang 325000, China

  • Received Date: 2012-12-07
  • Rev Recd Date: 2013-03-01
  • Objective To study the blood gas index and clinical effect of ulinastatin combined with non-invasive positive pressure ventilation in treatment of 36 acute lung injury patients. Methods AlI patients were collected and randomly divided into observation group given ulinastatin and NIPPV and control group given NIPPV. Then blood gas index and stress response were observed. Results PaO2, PaO2/FiO2, pH value of observation group were significantly higher than control group, PaCO2 was significantly lower than control group; glucose and insulin levels of observation recovered from the first day which were significantly earlier than control group. Conclusion The effect of ulinastatin combined with NIPPV had positive clinical value for the improvement of blood gas index and stress response.
  • [1] 中华医学会呼吸病学分会.急性肺损伤/急性呼吸窘迫综合征的诊断标准(草案)[S].中华结核和呼吸杂志,2000,23(4):203.
    [2] 薛新,刘志勇. 内毒素诱导急性肺损伤大鼠血清对内皮细胞通透性的影响及乌司他丁的保护作用研究[J].东南大学学报:医学版,2011,30(4):594.
    [3] 吴强,张泓,许启霞. 无创正压通气治疗急性肺损伤的临床研究[J].中华全科医学,2011,9(10):1501.
    [4] Meade MO,Cook DJ,Guyatt GH.Ventilation strategy using low tidal volumes, recruitment maneuvers,and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome:a randomized controlled trial[J].JAMA,2008,299(6):637.
    [5] 梁大胜,杜正隆,曾红. 乌司他丁治疗急性肺损伤31例临床观察[J].广西医科大学学报,2011,28(1):125.
    [6] 魏磊,刘标,梁永年. 乌司他丁在体外循环中肺保护机制的研究[J].中国体外循环杂志,2009,3(1):23.
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Blood gas index analysis and clinical effect comparison of ulinastatin combined with NIPPV in treatment of 18 ALI patients

doi: 10.3969/j.issn.1006-0111.2013.03.013
  • Department of Respiratory, the people's Hospital of Wenzhou, Zhejiang 325000, China
  • Received Date: 2012-12-07
  • Rev Recd Date: 2013-03-01

Abstract: Objective To study the blood gas index and clinical effect of ulinastatin combined with non-invasive positive pressure ventilation in treatment of 36 acute lung injury patients. Methods AlI patients were collected and randomly divided into observation group given ulinastatin and NIPPV and control group given NIPPV. Then blood gas index and stress response were observed. Results PaO2, PaO2/FiO2, pH value of observation group were significantly higher than control group, PaCO2 was significantly lower than control group; glucose and insulin levels of observation recovered from the first day which were significantly earlier than control group. Conclusion The effect of ulinastatin combined with NIPPV had positive clinical value for the improvement of blood gas index and stress response.

QIAN Xiao-ying. Blood gas index analysis and clinical effect comparison of ulinastatin combined with NIPPV in treatment of 18 ALI patients[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 207-209. doi: 10.3969/j.issn.1006-0111.2013.03.013
Citation: QIAN Xiao-ying. Blood gas index analysis and clinical effect comparison of ulinastatin combined with NIPPV in treatment of 18 ALI patients[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(3): 207-209. doi: 10.3969/j.issn.1006-0111.2013.03.013
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