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Volume 31 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2013  >  31(2): 129-130,147

DENG Jing-jing, XU Juan, WU Ye, CHEN Jun-shi, YANG Feng. Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 129-130,147. doi: 10.3969/j.issn.1006-0111.2013.02.013
Citation: DENG Jing-jing, XU Juan, WU Ye, CHEN Jun-shi, YANG Feng. Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 129-130,147. doi: 10.3969/j.issn.1006-0111.2013.02.013
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Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil

doi: 10.3969/j.issn.1006-0111.2013.02.013

  • Center of experimental teaching, School of Pharmacy, Chengdu Medical College, Chengdu 610083, China

  • Received Date: 2012-05-10
  • Rev Recd Date: 2012-07-27
  • Objective To compare the methods of saturated water solution and ultrasonic for preparation inclusion compound of β-cyclodextrin with peppermint oil. Methods After extraction of peppermint oil, the inclusion compound of β-cyclodextrin with peppermint oil was prepared by saturated water solution method and ultrasonic method. Results The better inclusion method was saturated water solution with higher inclusion rate and yield of inclusion compound. And the optimum inclusion conditions were as follows:peppermint oil(ml):β-cyclodextrin(g)=1:5, stirring for 1 hour, 45℃, β-cyclodextrin(g):water(ml)=1:10. Conclusion The better inclusion method was saturated water solution which was reasonable and convenient.
  • [1] 叶卯祥,严雪黎.β-环糊精包合技术在中药挥发油制剂中的应用研究[J].医学综述, 2010,16(24):3793.
    [2] 罗国平,樊俊红.白术、枳实、玫瑰花挥发油-β-环糊精包合物的制备工艺研究[J].药品评价,2005,2(2):131.
    [3] 钟秀英.药用β-环糊精包合物制备、检验技术研究进展[J].中药材,2003,26(4):262.
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Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil

doi: 10.3969/j.issn.1006-0111.2013.02.013
  • Center of experimental teaching, School of Pharmacy, Chengdu Medical College, Chengdu 610083, China
  • Received Date: 2012-05-10
  • Rev Recd Date: 2012-07-27

Abstract: Objective To compare the methods of saturated water solution and ultrasonic for preparation inclusion compound of β-cyclodextrin with peppermint oil. Methods After extraction of peppermint oil, the inclusion compound of β-cyclodextrin with peppermint oil was prepared by saturated water solution method and ultrasonic method. Results The better inclusion method was saturated water solution with higher inclusion rate and yield of inclusion compound. And the optimum inclusion conditions were as follows:peppermint oil(ml):β-cyclodextrin(g)=1:5, stirring for 1 hour, 45℃, β-cyclodextrin(g):water(ml)=1:10. Conclusion The better inclusion method was saturated water solution which was reasonable and convenient.

DENG Jing-jing, XU Juan, WU Ye, CHEN Jun-shi, YANG Feng. Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 129-130,147. doi: 10.3969/j.issn.1006-0111.2013.02.013
Citation: DENG Jing-jing, XU Juan, WU Ye, CHEN Jun-shi, YANG Feng. Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 129-130,147. doi: 10.3969/j.issn.1006-0111.2013.02.013
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