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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(5): 365-368

ZHANG Hai-hong, LIU Fang. The stability of compatibility of carbazochrome sodium sulfonate with four transfusions in common use[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 365-368. doi: 10.3969/j.issn.1006-0111.2012.05.013
Citation: ZHANG Hai-hong, LIU Fang. The stability of compatibility of carbazochrome sodium sulfonate with four transfusions in common use[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 365-368. doi: 10.3969/j.issn.1006-0111.2012.05.013
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The stability of compatibility of carbazochrome sodium sulfonate with four transfusions in common use

doi: 10.3969/j.issn.1006-0111.2012.05.013
  • 1.

    Department of Pharmacy, Zhejiang ShengSi People's Hospital, Shengsi 202450, China

  • 2.

    Institute of Matera Medica, Zhejiang Academy of Medical Sciences, Hangzhou 310013, China

  • Received Date: 2011-12-12
  • Rev Recd Date: 2012-03-27
  • Objective To study the stability of compatibility of carbazochrome sodium sulfonate with four different transfusions for 6 hours at room temperature. Methods The content and related substances of carbazochrome sodium for sulfonate injection in four mixture were determined by UV spectrophotometric and HPLC. The appearance and pH values were determined. Results TThe results showed that there was no significant changes after matching in the appearance, pH values, content and related substances for 6 hours at room temperature. Conclusion Carbazochrome sodium sulfonate for injection could be combined with 5% glucose injection, 10% glucose injection, 0.9% sodium chloride injection, glucose and sodium choloride injection.
  • [1] 王泽民. 当代药物结构全集[M]. 北京:北京科技出版社,1993:1567.
    [2] 国家药典委员会. 国家药品监督管理局化学药品地方标准上升国家标准[S]. 第3册:2002:65.
    [3] 国家药典委员会. 国家药品监督管理局国家药品标准新药转正标准[S]. 第24册:2001:879.
    [4] 纪标,王东顺,高斐,等. 测定卡络磺钠注射液的含量和有关物质[J]. 沈阳药科大学学报,2006,23(3):159.
    [5] 黄顺旺,许龙,曹明成. HPLC法测定卡络磺钠葡萄糖注射液中卡络磺钠的含量[J]. 安徽医药,2008,12(2):120.
    [6] 刘伟,周伯庭,徐平声. 高效液相色谱法测定注射用卡络磺纳中卡络磺纳的含量[J]. 中国药房,2005,16(15):1175.
    [7] 陈莉,崔颖,段姚尧. 高效液相色谱法测定注射用卡络磺钠原料药的含量[J]. 武警医学院学报,2008,17(2):90.
    [8] 陈新谦,金有豫,汤光. 新编药物学[M].第15版. 北京:人民卫生出版社,2003:524.
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The stability of compatibility of carbazochrome sodium sulfonate with four transfusions in common use

doi: 10.3969/j.issn.1006-0111.2012.05.013
  • 1. Department of Pharmacy, Zhejiang ShengSi People's Hospital, Shengsi 202450, China
  • 2. Institute of Matera Medica, Zhejiang Academy of Medical Sciences, Hangzhou 310013, China
  • Received Date: 2011-12-12
  • Rev Recd Date: 2012-03-27

Abstract: Objective To study the stability of compatibility of carbazochrome sodium sulfonate with four different transfusions for 6 hours at room temperature. Methods The content and related substances of carbazochrome sodium for sulfonate injection in four mixture were determined by UV spectrophotometric and HPLC. The appearance and pH values were determined. Results TThe results showed that there was no significant changes after matching in the appearance, pH values, content and related substances for 6 hours at room temperature. Conclusion Carbazochrome sodium sulfonate for injection could be combined with 5% glucose injection, 10% glucose injection, 0.9% sodium chloride injection, glucose and sodium choloride injection.

ZHANG Hai-hong, LIU Fang. The stability of compatibility of carbazochrome sodium sulfonate with four transfusions in common use[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 365-368. doi: 10.3969/j.issn.1006-0111.2012.05.013
Citation: ZHANG Hai-hong, LIU Fang. The stability of compatibility of carbazochrome sodium sulfonate with four transfusions in common use[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 365-368. doi: 10.3969/j.issn.1006-0111.2012.05.013
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